验光单上面KRT.DATA下面的数据代表什么？ - 知乎

验光单上面KRT.DATA下面的数据代表什么？ - 知乎首页知乎知学堂发现等你来答​切换模式登录/注册数据数据分析工具验光验光单上面KRT.DATA下面的数据代表什么？这里面D、MM、A、MM1、MM2、A1分别代表什么意思呢？对配眼镜是否有影响呢？如图 [图片]显示全部 ​关注者10被浏览111,932关注问题​写回答​邀请回答​好问题 1​1 条评论​分享​5 个回答默认排序视光师黄素依​视光行业里默默耕耘着​ 关注这是电脑验光单数据(客观验光数据)用于初步了解眼睛度数情况。主要说一下框框内的数据:R代表右眼，L代表左眼;D那一栏是指角膜的屈光度，正常范围一般为43.05D;MM那一栏是指角膜前表面的曲率半径，验配隐形眼镜选择基弧时就是参考这个值来计算的;A那一栏代表的是角膜屈光度所在的方向;R1是水平向;R2是垂直向;AVE是水平与垂直的平均值;拿右眼来说:水平:角膜屈光度42.50D@166，垂直:角膜屈光度43.75D@76，从这两数据可以看出角膜散光有1.25D，轴在166;这个值可以与综合验光仪验出来的散光做比对，看你的散光是角膜散光还是眼内散光;另外，通过角膜屈光度这个值可以评估你的近视是轴性近视还是曲率性近视。从这单子上的数据看，你的近视是轴性近视，而且已经是高度近视，提示要关注眼底情况了，至少要拍个眼底照片、测个眼轴长度。大多数人只关注电脑验光单上的近视、散光这些数据，其实这张单的其他数据不管对于验光师还是被检者来说都挺有用的。有用的话，记得关注我哦，带你了解更多编辑于 2021-05-04 18:17​赞同 37​​2 条评论​分享​收藏​喜欢收起​武汉配镜点亮哥​武汉市洪山区亮哥点亮眼镜工作室 经营者​ 关注电脑验光数据，一般作为客观（他觉）验光的参考，实际配镜需与主观验光相结合，所谓主观验光就是以“你问我答”的形式通过辨认视力表以及相关测试进行有效、相互沟通，最终确定更为合适的配镜数据。此单除了参考的验光数据外还包括左右眼的一个曲率、曲率半径（比如部分需要配定制的隐形眼镜的参考）。编辑于 2021-05-03 15:55​赞同 1​​添加评论​分享​收藏​喜欢

急性肾损伤的血液透析和滤过 | 《新英格兰医学杂志》综述

急性肾损伤的血液透析和滤过 | 《新英格兰医学杂志》综述

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找到一个基因家族，基本上可以坐等发SCI - 知乎

找到一个基因家族，基本上可以坐等发SCI - 知乎首发于SCI狂人团队切换模式写文章登录/注册找到一个基因家族，基本上可以坐等发SCISCI狂人团队今天分享一篇基因家族的纯生信文章，可以说找到一个没有人做过数据挖掘的基因家族，基本上就是坐等发SCI。今天介绍这篇参考文章发表在Scientific Reports 上，江湖人称“四大神刊”之一，影响因子：3.988，从15年的5.228跌到现在的3.988，经典的OA期刊。参考范文来源：PMID: 33441834 DOI: 10.1038/s41598-020-80336-8。研究背景：角蛋白（KRTs）是上皮细胞的中间细丝形成蛋白，被广泛用作癌症的诊断生物标志物，并与多种癌症的肿瘤发生和转移有关。然而，KRTs在黑色素瘤中的多种表达模式和预后价值尚未阐明。研究方法：在本研究中，我们利用来自GEO，TCGA，ONCOMINE，GEPIA，cBioPortal，TIMER和TISIDB数据库的黑色素瘤患者KRT的转录数据和临床数据进行分析。研究结果：我们发现，KRT1 / 2/5/6/8/10/14/15/16/17的mRNA水平在原发性黑色素瘤和转移性黑色素瘤之间表达差异显着。KRT1 / 2/5/6/10/14/15/16/17的表达水平与肿瘤的晚期分期有关。生存分析表明，KRT1 / 5/6/14/15/16/17的高转录水平与黑色素瘤患者的总生存率低有关。GSEA分析表明，最参与的标志性通路是P53通路，KRAS信号传导，早期雌激素反应和晚期雌激素反应。此外，我们发现KRTs的表达与免疫细胞的浸润之间存在一些相关性。研究结论：我们的研究可能为黑色素瘤预后生物标志物的选择提供新颖的见解。今天分享一篇基因家族的纯生信文章，可以说找到一个没有人做过数据挖掘的基因家族，基本上就是坐等发SCI。今天介绍这篇参考文章发表在Scientific Reports 上，江湖人称“四大神刊”之一，影响因子：3.988，从15年的5.228跌到现在的3.988，经典的OA期刊。参考范文来源：PMID: 33441834 DOI: 10.1038/s41598-020-80336-8。分析思路：1、利用GEPIA在线数据库分析KRTs家族成员在SKCM中的基因表达水平2、利用Oncomine在线数据库进行KRTs家族成员在pan-cancer基因表达情况分析和生存分析3、分析KRTs家族成员在SKCM中基因表达水平与临床病理参数的相关性4、利用SKCM临床数据对KRTs家族成员进行生存分析，寻找有预后价值的成员5、分析KRTs家族成员在SKCM中的蛋白表达水平6、对KRTs家族成员进行功能分析（GO、通路、PPI、免疫相关性）总结：简单的地方：这篇文章利用ONCOMINE，GEPIA，cBioPortal，TIMER和TISIDB等在线数据库进行操作分析，既简单又快捷方便（零代码操作）。比较难的地方：如何发现这样一个没有人做过数据挖掘的基因家族。补充内容：1、没有经费的玩法：利用TCGA数据将这些有预后价值的家族成员构建模型，计算risk score，并且将risk score结合临床因素进行分析。2、有经费的玩法：补充自己的测序数据和功能实验，探索这些家族成员的作用机制。发布于 2021-01-17 10:10SCI 论文数据挖掘生物信息学​赞同 22​​3 条评论​分享​喜欢​收藏​申请转载​文章被以下专栏收录SCI狂人团队手把手教你

角蛋白 10（KRT10）基因 | MCE

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Gene

KRT10 - keratin 10 Gene

KRT10 - keratin 10 Gene

基因

蛋白

疾病

相关产品

直系同源

中文名称：角蛋白 10

种属: Homo sapiens

同用名: BIE; EHK; IHL; K10; KPP; BCIE; CK10

基因 ID: 3858

|

基因类型: protein coding

关于 KRT10

Cytogenetic location: 17q21.2

Genomic coordinates (GRCh38): 17:40,818,117-40,822,614 (from NCBI)

This gene has 2 transcripts (splice variants), 104 orthologues, 68 paralogues and is associated with 9 phenotypes. Restricted expression toward skin (RPKM 7171.9).

功能概要

该基因编码 I 型 (酸性) 细胞角蛋白家族的成员，属于中间丝 (IF) 蛋白超家族。角蛋白是形成中间丝的杂聚结构蛋白。这些细丝与肌动蛋白微丝和微管一起构成了上皮细胞的细胞骨架。该基因的突变与表皮松解性角化过度有关。该基因位于染色体 17q21 上的角蛋白家族成员簇内。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the Cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]

KRT10 基因产物(2)

mRNA

Protein

Name

NM_000421.5

NP_000412.4

keratin, type I cytoskeletal 10 isoform 1

NM_001379366.1

NP_001366295.1

keratin, type I cytoskeletal 10 isoform 2

KRT10 蛋白结构

Filament

Filament: Intermediate filament protein (145 - 458)

0

100

200

300

400

500

584 a.a.

蛋白主名

其他名称

keratin, type I cytoskeletal 10

CK-10

关联疾病

疾病名称

别名

Ichthyosis, Cyclic, With Epidermolytic Hyperkeratosis

AEI

Annular Epidermolytic Ichthyosis

Epidermolytic Ichthyosis, Annular

Ciehk

Ichthyosis Annular Epidermolytic

Annular Ichthyosis Variant Of Bcie

Cyclic Ichthyosis With Epidermolytic Hyperkeratosis

Ichthyosis With Confetti

Congenital Reticular Ichthyosiform Erythroderma

IWC

CRIE

Erythroderma, Ichthyosiform, Congenital Reticular

Ichthyosis Variegata

Erythrokeratoderma, Reticular

Ichthyosis Variegata Micropinnae, Alopecia Universalis, Congenital Ichthyosis, And Ectropion

Mauie

Mauie Syndrome

Aarau Disease

Reticular Erythrokeratoderma

Epidermolytic Hyperkeratosis

Bullous Congenital Ichthyosiform Erythroderma

Bullous Ichthyosiform Erythroderma

EHK

Bullous Erythroderma Ichthyosiformis Congenita Of Brocq

Bcie

Bie

Epidermolytic Ichthyosis

Ichthyosis Bullosa Of Siemens

Superficial Epidermolytic Ichthyosis

Hyperkeratosis, Epidermolytic

Congenital Bullous Ichthyosiform Erythroderma

Bullous Type Ichthyosis

Epidermolytic Palmoplantar Hyperkeratosis

Bullous Ichthyosiform Erythroderma Congenita

Bullous Erythroderma Ichthyosiforme

Sei

Epidermolytic Hyperkeratosis Late-Onset

Epidermolytic Hyperkeratosis, Late-Onset

Autosomal Recessive Epidermolytic Ichthyosis

Arei

Autosomal Dominant Epidermolytic Ichthyosis

Bcie

Bullous Congenital Ichthyosiform Erythroderma

Bullous Congenital Ichthyosiform Erythroderma Of Brock

Bullous Ichthyosis

Ehk

Ei

Epidermolytic Hyperkeratosis

Ichthyosis Hystrix Brocq Type

Epidermolytic Acanthoma

Keratosis

Actinic Keratosis

Hyperkeratosis

Steatocystoma Multiplex

Sebocystomatosis

Multiple Sebaceous Cysts

Multiplex Steatocystoma

Sebaceous Cysts, Multiple

SM

Acanthoma

Ichthyosis

Ichthyoses

Non-Syndromic Ichthyosis

Congenital Ichthyosis

Epidermolysis Bullosa Simplex

Ebs

Epidermolysis Bullosa Intraepidermic

Epidermolytic Epidermolysis Bullosa

Keratoacanthoma

Ka - [Keratoacanthoma]

Well-Differentiated Squamous Cell Carcinoma

Bowen'S Disease

Bowens Disease

Papilloma

Papillomatosis

Mucinous Tubular And Spindle Renal Cell Carcinoma

Mucinous Tubular And Spindle Cell Renal Carcinoma

Lichen Planus

Lichen Ruber Planus

Lichen, Ruber Planus

Ruber Planus

Lp - [Lichen Planus]

Lichen Planus Of Wilson

Wilson Lichen Ruber

Large Cell Acanthoma

Ichthyosis Bullosa Of Siemens

IBS

Ichthyosis, Bullous Type

Bullous Type Of Ichthyosis

Ichthyosis Bullous Type

Skin Disease

Skin Diseases

Genodermatosis

Abnormality Of The Skin

Skin Diseases, Genetic

Skin And Subcutaneous Tissue Disease

Dermatologic Disorders

Cholesteatoma Of Middle Ear

Cholesteatoma

Epidermosis Of Ear

Epidermosis Of Middle Ear

Middle Ear Cholesteatoma

Cholesteatoma Of Middle Ear And Mastoid

Cholesteatoma Of Middle Ear And/Or Mastoid

Cholesteatoma Of The Middle Ear

Congenital Cholesteatoma

Primary Acquired Cholesteatoma

Secondary Acquired Cholesteatoma

Cholesteatoma Middle Ear

Cholesteatoma, Middle Ear

Cholesterolosis Of Middle Ear

Cholesterosis Of Ear

Cholesterosis Of Middle Ear

Cholesteatoma Nos

Epidermoid Cholesteatoma

Middle Ear Granuloma

Palmoplantar Keratosis

Palmoplantar Keratoderma

Keratosis Palmaris Et Plantaris

Palmo-Plantar Keratodermas

Keratoderma, Palmoplantar

Keratoderma Palmoplantar

Keratoderma, Palmoplantar, Diffuse

Hyperkeratosis Of Palms And Soles

Palmoplantar Hyperkeratosis

Clear Cell Acanthoma

Acanthoma

Pale Acanthoma

Acanthoma, Clear Cell

Epidermolysis Bullosa

Acantholysis Bullosa

Eb

Borst-Jadassohn Intraepidermal Carcinoma

Intraepidermal Epithelioma Of Jadassohn

Bowen'S Disease, Clonal

Psoriasis

Hidradenitis Suppurativa

Acne Inversa

Suppurative Hidradenitis

Acne Inversa, Familial

Apocrinitis

Hidradenitides, Suppurative

Hidradenitis, Suppurative

Suppurative Hidradenitides

Inverse Acne

Endocarditis

Keratosis, Seborrheic

Seborrheic Keratosis

Keratosis, Seborrheic, Somatic

Basal Cell Papilloma

Keratosis Seborrheica

KERSEB

Nevus, Epidermal

Epidermal Nevus

Woolly Hair Nevus

Epidermal Naevus

Epidermal Nevus Syndrome

Nevus, Keratinocytic, Nonepidermolytic

Epidermal Nevus, Somatic

Nevus, Epidermal, Somatic

Nevus Sebaceous Or Woolly Hair Nevus, Somatic

Nonepidermolytic Keratinocytic Nevus

Epidermal Hamartoma Syndrome

Wooly Hair Nevus

Keratinocytic Non-Epidermolytic Nevus

KNEN

Pigmented Moles

Organoid Nevus Phakomatosis

Nevus Sebaceous

Melanocytic Nevus

Melanocytic Nevus Of Skin

Palmoplantar Keratoderma, Epidermolytic

Epidermolytic Palmoplantar Keratoderma

EPPK

Keratosis Palmaris Et Plantaris Familiaris

Tylosis

Keratosis Of Greither

Diffuse Nonepidermolytic Palmoplantar Keratoderma

Keratoderma, Palmoplantar, Epidermolytic

Unna-Thost Palmoplantar Keratoderma

Epidermolytic Palmoplantar Keratoderma Of Voerner

Ppke

Keratoderma, Epidermolytic Palmoplantar

Palmoplantar Keratoderma, Vorner Type

Hyperkeratosis, Localized Epidermolytic

Diffuse Erythrodermic Palmoplantar Keratoderma, Vörner Type

Epidermolytic Palmoplantar Keratoderma Of Vörner

Hyperkeratosis Palmoplantar Localized Epidermolytic

Diffuse Neppk

Ppk Diffusa Circumscripta

Thost-Unna Disease

Thost-Unna Palmoplantar Keratoderma

Diffuse Erythrodermic Palmoplantar Keratoderma, Voerner Type

Diffuse Erythrodermic Palmoplantar Keratoderma, Vorner Type

Epidermolytic Palmoplantar Keratoderma Of Vorner

Ehppk

Epidermolytic Unna-Thost Disease

Localized Epidermolytic Hyperkeratosis

Palmoplantar Keratoderma Vorner Type

Unilateral Palmoplantar Verrucous Nevus

UPVN

Keratoderma, Palmoplantar, Diffuse

Hyperkeratosis

Palmoplantar Keratoderma, Nonepidermolytic

Epidermolytic Palmoplantar Keratoderma Vorner Type

Type B Tylosis

Hyperkeratosis Of The Palms And Soles And Esophageal Papillomas

Type A Tylosis

Nodular Hidradenoma

Eccrine Nodular Hidradenoma

Eccrine Acrospiroma

Pulmonary Artery Leiomyosarcoma

Leiomyosarcoma Of The Pulmonary Artery

Pachyonychia Congenita 1

Pachyonychia Congenita

Jadassohn-Lewandowsky Syndrome

Pachyonychia Congenita Syndrome

PC1

Pachyonychia Congenita, Jadassohn-Lewandowsky Type

Congenital Pachyonychia

Pachyonychia Congenita, Type 1

Pachyonychia Congenita, Jadassohn-Lewandowsky Type, Formerly

Jadassohn-Lewandowsky Syndrome, Formerly

Jackson-Lawler Type Pachyonychia Congenita

Pachyonychia Congenita Type 1

Jackson-Lawler Syndrome

Jadassohn-Lewandowski Syndrome

Pc

Pachyonychia Congenita Jackson-Lawler Type

Pachyonychia Congenita Jadassohn-Lewandowsky Type

Pachyonychia Congenita Jackson Lawler Type

Pc-1

Pachyonychia Congenita, Jadassohn Lewandowsky Type

Pachyonychia Congenita, Type 2

Eccrine Papillary Adenoma

Papillary Eccrine Adenoma

Eccrine Papillary Adenoma Of Skin

Trichothiodystrophy 1, Photosensitive

TTD1

Tay Syndrome

Trichothiodystrophy With Congenital Ichthyosis

Photosensitive Trichothiodystrophy

Ibids Syndrome

Ttdp

Ichthyosiform Erythroderma With Hair Abnormality And Mental And Growth Retardation

Ichthyosis, Congenital, With Trichothiodystrophy

Pibids Syndrome

Photosensitive Trichothiodystrophy 1

Trichothiodystrophy, Photosensitive

Sulfur-Deficient Brittle Hair Syndrome

Ttd-P

Ichthyosis With Brittle Hair, Intellectual Impairment, Decreased Fertility And Short Stature

Trichothiodystrophy Photosensitive

Trichothiodystrophy, Type 1

Tricho-Thiodystrophy Disorder

Trichothiodystrophy Syndromes

Amish Brittle Hair Brain Syndrome

Skin Papilloma

Cutaneous Papilloma

Papilloma Of Skin

Papilloma Skin

Vohwinkel Syndrome

Mutilating Keratoderma

Keratoderma Hereditarium Mutilans

Khm

VOWNKL

Deafness, Congenital, With Keratopachydermia And Constrictions Of Fingers And Toes

Mutilating Keratoderma Of Vohwinkel

Mutilating Keratoderma Plus Deafness

Ppk Mutilans And Deafness

Congenital Deafness With Keratopachydermia And Constrictions Of Fingers And Toes

Congenital Deafness With Keratopachydermia And Constrictions Fo Fingers And Toes

Palmoplantar Keratoderma Mutilans

Palmoplantar Keratoderma Mutilans Vohwinkel

Ppk Mutilans Vohwinkel

Mutilating Keratoderma Plus Hearing Loss

Ppk Mutilans And Hearing Loss

Eccrine Sweat Gland Neoplasm

Eccrine Skin Neoplasm

Eccrine Tumor

Eccrine Neoplasm

Malignant Eccrine Neoplasm

Ectodermal Dysplasia 9, Hair/Nail Type

ECTD9

Ectodermal Dysplasia 9

Dysplasia, Ectodermal, Type 9, Hair/Nail

Malignant Biphasic Mesothelioma

Mesothelioma, Biphasic, Malignant

Mixed Mesothelioma

Clear Cell Hidradenoma

Clear Cell Myoepithelioma

Eccrine Acrospiroma

Ichthyosis Vulgaris

Ichthyosis Simplex

Dominant Congenital Ichthyosiform Erythroderma

Common Ichthyosis

Fish Scale Disease

VI

Ichthyoses

Congenital Ichthyosis

Toxicodendron Dermatitis

Dermatitis, Toxicodendron

Contact Dermatitis Due To Genus Toxicodendron

Rhus Dermatitis

Dermatitis Toxicodendron

Eccrine Acrospiroma

Acrospiroma

Poroma

Eccrine Hidradenoma

Eccrine Hidradenoma Of Skin

Hidradenoma

Adenoma, Sweat Gland

Benign Neoplasm Of Sweat Gland

Eccrine Poroma

Actinic Keratosis

Solar Keratosis

Actinic Keratosis

Senile Hyperkeratosis

Sk - Solar Keratosis

Keratosis, Actinic

Seborrheic Keratosis

Ak - [Actinic Keratosis]

Sk - [Solar Keratosis]

Erythrokeratodermia Variabilis Et Progressiva 1

Erythrokeratodermia Variabilis

Erythrokeratodermia Variabilis Et Progressiva

Greither Disease

Ekv

Ekvp

PSEK

Erythrokeratodermia Variabilis With Erythema Gyratum Repens

Keratosis Palmoplantaris Transgrediens Et Progrediens

Transgrediens Et Progrediens Palmoplantar Keratoderma

EKVP1

Erythrokeratodermia, Progressive Symmetric

Erythrokeratodermia Figurata, Congenital Familial, In Plaques

Keratoderma Palmoplantaris Transgrediens

Keratosis Extremitatum Hereditaria Progrediens

Erythrokeratodermia Variabilis, Mendes Da Costa Type

Progressive Symmetric Erythrokeratodermia

Erythrokeratodermia Figurata Variabilis

Greither'S Disease

Ekv-P

Erythrokeratodermia Variabilis Of Mendes Da Costa

Progressive Symmetrical Erythrokeratoderma Of Gottron

Progressive Diffuse Ppk

Progressive Diffuse Palmoplantar Keratoderma

Transgrediens Et Progrediens Ppk

Darier-Gottron Disease

Erythrokeratodermia Progressiva Symmetrica

Progressive Symmetric Erythrokeratodermia, Gottron Type

Congenital Familial Erythrokeratodermia Figurata In Plaques

Erythrokeratodermia Progressive Symmetric

Erythrokeratodermia Variabilis Mendes Da Costa Type

Ichthyosis, Congenital, Autosomal Recessive 4b

Harlequin Ichthyosis

Autosomal Recessive Congenital Ichthyosis 4b

Hi

Harlequin Fetus

ARCI4B

Ichthyosis Congenita, Harlequin Fetus Type

Harlequin Type Ichthyosis

'Harlequin Fetus'

Harlequin Type Ichthyosis Congenita

Harlequin Type Ichthyosis Fetalis

Harlequin Baby Syndrome

Ichthyosis Congenita, Harlequin Type

Ichthyosis Fetalis, Harlequin Type

Ichthyosis Congenita Harlequin Fetus Type

Ichthyosis, Harlequin

Ichthyosis, Congenital, Autosomal Recessive, Type 4b

Basal Cell Carcinoma

Basal Cell Cancer

Basal Cell Neoplasm

Basal Cell Carcinoma Of Skin

Malignant Basal Cell Tumor

Basal Cell Tumor

Epithelioma Basal Cell

Malignant Basal Cell Neoplasm

Rodent Ulcer

Carcinoma Basal Cell

Neoplasms, Basal Cell

Basal Cell Carcinomas

Experimental Organism Basal Cell Carcinoma

Nodulo-Ulcerative Basal Cell Carcinoma

Basalioma

Basal Cell Epithelioma Of Skin

Bcc - [Basal Cell Carcinoma] Of Skin

Rodent Ulcer Of Skin

Rodent Ulcer Of Unspecified Site

Basal Cell Epithelioma Of Unspecified Site

Epidermolysis Bullosa Simplex 1a, Generalized Severe

Epidermolysis Bullosa Simplex, Dowling-Meara Type

Epidermolysis Bullosa Herpetiformis, Dowling-Meara Type

EBS1A

Ebsdm

Epidermolysis Bullosa Simplex Dowling-Meara Type

Epidermolysis Bullosa Simplex, Herpetiformis

Ebs-Dm

Epidermolysis Bullosa Simplex 1a, Dowling-Meara Type

Ebs-Gen Sev

Epidermolysis Bullosa Herpetiformis Dowling-Meara Type

Generalized Severe Epidermolysis Bullosa Simplex

Dowling-Meara Type Epidermolysis Bullosa Simplex

Autosomal Dominant Generalized Epidermolysis Bullosa Simplex, Severe Form

Autosomal Dominant Generalized Ebs, Severe Form

Epidermolysis Bullosa Simplex Herpetiformis

Dm-Ebs

Epidermolysis Bullosa Simplex, Generalized Severe

Epidermolysis Bullosa Herpetiformis, Dowling-Meara

Epidermolysis Bullosa Herpetiformis Dowling-Meara

Cervical Squamous Cell Carcinoma

Squamous Cell Carcinoma Of The Cervix Uteri

Squamous Cell Carcinoma Of Cervix

Hair Follicle Neoplasm

Hair Matrix Neoplasm

Hair Matrix Tumour

Benign Chronic Pemphigus

Hailey-Hailey Disease

Pemphigus, Benign Familial

Familial Benign Pemphigus

Benign Familial Pemphigus

Familial Benign Chronic Pemphigus

BCPM

HHD

Benign Chronic Familial Pemphigus Of Hailey-Hailey

Pemphigus, Chronic, Benign

Autosomal Recessive Congenital Ichthyosis

Lamellar Ichthyosis

Congenital Ichthyosiform Erythroderma

Li

Congenital Nonbullous Ichthyosiform Erythroderma

Arci

Congenital Lamellar Ichthyosis

Nonbullous Congenital Ichthyosiform Erythroderma

Cie

Congenital Non-Bullous Ichthyosiform Erythroderma

Erythrodermic Ichthyosis

Nbcie

Ncie

Non-Bullous Congenital Ichthyosiform Erythroderma

Collodion Baby

Ichthyosis, Lamellar

Non Bullous Congenital Ichthyosiform Erythroderma

Ichthyosiform Erythroderma, Brocq Congenital, Nonbullous Form

Ichthyosiform Erythroderma, Congenital, Nonbullous, 1

Collodion Baby Syndrome

Ichthyoses, Lamellar

Nbie

Nonbullous Ichthyosiform Erythroderma

Classic Lamellar Ichthyosis

Ichthyosiform Erythroderma Nonbullous Congenital

Ichthyosiform Erythroderma Congenital

Ichthyosis, Congenital, Autosomal Recessive

Ichthyosiform Erythroderma, Congenital

Collodion Fetus

Non-Bullous Ichthyosiform Erythroderma

Skin Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Skin

Epidermoid Skin Carcinoma

Squamous Cell Carcinoma Of The Skin

Squamous Cell Epithelioma Of Skin

Cutaneous Squamous Cell Carcinoma

Scc - [Squamous Cell Carcinoma] Of Skin

Epidermolysis Bullosa Simplex Localized Type

Epidermolysis Bullosa Simplex, Weber-Cockayne Type

Weber-Cockayne Syndrome

Ebs-Loc

Epidermolysis Bullosa Simplex Of Palms And Soles

Epidermolysis Bullosa Simplex Weber-Cockayne Type

Epidermolysis Bullosa Simplex, Localized

Epidermolysis Bullosa Of Hands And Feet

Weber-Cockayne Type Epidermolysis Bullosa Simplex

Localized Epidermolysis Bullosa Simplex

Localized Ebs

Porokeratosis

Disseminated Superficial Actinic Porokeratosis

Dsap

Porokeratosis Of Mibelli

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细胞角蛋白7的表达在肿瘤及炎症中的意义 - 国际免疫学杂志

细胞角蛋白7的表达在肿瘤及炎症中的意义 - 国际免疫学杂志

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• 综述 •

细胞角蛋白7的表达在肿瘤及炎症中的意义

谢佳佳

郭晓华

国际免疫学杂志, 2016,39(1)

: 57-60. DOI: 10.3760/cma.j.issn.1673-4394.2016.01.013

摘要细胞角蛋白(Krt)作为一种中间丝，存在于所有的上皮细胞及部分非上皮细胞。主要作用是维持上皮细胞的机械稳定性和完整性。近年来细胞角蛋白的研究集中在肿瘤的诊断方面，即利用细胞角蛋白在上皮细胞表达的特异性，通过免疫组化技术，运用单克隆抗体进行比对分析，来确定肿瘤的分类、分型或者来源。其中Krt7是一个代表。探讨Krt7的作用，在上皮肿瘤中的分布，以及与细胞角蛋白20(Krt20)在上皮肿瘤中的联合表达情况，对肿瘤的诊断、转移性与原发肿瘤的鉴别等有重要意义。除此之外，Krt7还是一个炎性指标，发挥信号转导中的作用，参与炎症的发生发展，其表达也有利于对某些疾病早期及预后进行监测。

引用本文:

谢佳佳,

郭晓华.

细胞角蛋白7的表达在肿瘤及炎症中的意义

[J]

. 国际免疫学杂志, 2016, 39(1)

: 57-60.

DOI: 10.3760/cma.j.issn.1673-4394.2016.01.013.

参考文献导出:  

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细胞角蛋白作为一种中间丝，存在于所有的上皮细胞及部分非上皮细胞。人细胞角蛋白有20种，它们分为两组：Ⅰ型，酸性细胞角蛋白(Moll数为9～20)，28种；Ⅱ型，碱性细胞角蛋白(Moll数为1～8)，26种[1]。I型和II型配对形成多样性的聚合物。作为细胞骨架的一部分，细胞角蛋白在维持上皮细胞的机械稳定性和完整性上起着重要的作用。此外，一些细胞角蛋白也有监管和参与细胞内信号通路的作用，如保护机体免受压力、促进伤口愈合等。它们的表达参与了细胞结构调控、生长、增殖和凋亡[1,2]。另外，细胞角蛋白在人类肿瘤中也呈现出特定的表达模式，尤其是Ⅰ型如K18、K19和K20，Ⅱ型如K5、K7、K8等，它们所在的上皮肿瘤及其转移瘤仍然保留原先的表达模式[3,4]。因而细胞角蛋白在肿瘤的免疫组化诊断、肿瘤的转移和分类以及亚型确定等方面起着重要作用。在众多细胞角蛋白中，Krt7是其中的一个代表，不仅因为它在肿瘤中的表达具有较高的特异性，其在炎症中也扮演着越来越重要的角色。

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贡献者信息

谢佳佳

510515　广州，南方医科大学病理生理学教研室

郭晓华

510515　广州，南方医科大学病理生理学教研室

通信作者

郭晓华

510515　广州，南方医科大学病理生理学教研室

Email：lanblue@fimmu.com

关键词

细胞角蛋白7;

肿瘤;

炎症;

基金项目

国家自然科学基金青年基金

（31300950）

教育部博士点博士学科点专项科研基金联合资助课题新教师类

（20124433120011）

历史

出版日期：2016-01-05

收稿日期：2015-07-19

Review

The meaning of keratin-7 expression in cancer and inflammation

XIE Jiajia,  GUO Xiaohua

Published 2016-01-05

Cite as Int J Immunol, 2016, 39(1): 57-60. DOI: 10.3760/cma.j.issn.1673-4394.2016.01.013

Abstract

Keratins(Krt) are the typical intermediate filament proteins of epithelia.As part of the epithelial cytoskeleton, keratins are important for the mechanical stability and integrity of epithelial cells and tissues.Recent researches focus on the diagnostics value of carcinomas, for they have characteristic expression patterns in human tumors.Besides, immunohistochemistry(IHC) and monoclonal antibodies can be helpful to identify tumors’ classification as well as their origin.Different immunophenotypes are associated with different carcinomas.Keratin-7(Krt7) is one of a representative protein among those keratins.A particularly useful IHC panel consists of anti-keratin 7 and anti-keratin 20 (Krt7/Krt20) antibodies.In addition, Krt7 is also an inflammatory factor in organ damage, which has been shown to have diagnostic and prognostic value in particular diseases.

Key words:

Keratin-7; Cancer; Inflammation

Contributor Information

XIE Jiajia

Department of Pathaphysiology of Southern Medical University, Guangzhou 510515, China

GUO Xiaohua

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出    处：国际免疫学杂志2016年39卷1期

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角蛋白(Keratin)介绍 - 知乎

角蛋白(Keratin)介绍 - 知乎切换模式写文章登录/注册角蛋白(Keratin)介绍毕合生物专注于生命科学、高端化学、药物中间体的自主研发，生产销售服务角蛋白分为表皮角蛋白和细胞角蛋白两种，这是根据其分部的部位而分的。表皮角蛋白包括皮肤表皮，消化道粘膜上皮、腺上皮甲状腺滤泡上皮、气管、支气管上 皮、肺泡上皮，角膜上皮、前列腺上皮等。细胞角蛋白包括颌下腺，胰腺，胸腺，细胞，肝细胞，肾小管细胞等。目前，应用上述细胞中间丝角蛋白作为抗原所制备 的抗体有单克隆抗体和多克隆抗体。角蛋白可有19个亚型 ，分为碱性和酸性，从1-8为碱性，9-19为酸性，分子量40-68不等，复层鳞上皮多为高分子量，单层上皮则多为低分子量，了解这些在临床的鉴别诊断 及抗体的应用中都 有极大的帮助。目前，检测这类特质的抗体很多，根据不同的克隆生产出不周类型的抗体。常用的抗体有：①单克隆小鼠抗人细胞角蛋白(Monoclonal mouse anti human cytokeratin)克隆为MNF116。该抗体应用范围，各类的冰冻切片，涂片，细胞培养片和经甲醛固定石蜡包埋的组织切片 。用本抗体检测的阳性组织有：鳞状上皮，甲状腺滤泡上皮消化道上皮，胰腺胆管上皮，肝胆管上皮，角膜上皮等以及发生于上述来源的肿瘤。应该注意的是有一些 肿瘤在检测时，可出现两种阳性物，即用两种抗体来检测如采用CK和Vimentin，可出现双向表达阳性的肿瘤有：癌内瘤，子宫内膜腺癌肺腺癌，上皮样内 瘤，滑膜内瘤，唾液腺肌上皮瘤，间皮瘤等等。这是由于在这些肿瘤中存在着两种不同的中间丝的缘故。应用该抗体检测呈阴性的肿瘤有：各种淋巴瘤，各类肌源性的肿瘤，恶性黑色素瘤，骨肿瘤，纤维组织肿瘤，脂肪肿瘤，神经组织肿瘤和精原细胞瘤等。在检测某些肿瘤时，常可出现这样的问题，在同一张切片上，同样的鳞状细胞癌的细胞，有的抗原表达为强阳性，有的表达为中度阳性性，有的表达为弱阳性，甚至有的呈阴性。这主要是由于各种细胞处于增生的不同阶段，细胞分泌的抗原量不同，因而表达 也不同。该抗体可用各种方法检测，但最好用真空负压LSAB法。产品说明书注明该抗体稀释度1：50至1：100，我们使用为1：100。②单克隆小鼠抗人细胞角蛋白，克隆为LP34。该抗体的使用范围，检测各种组织基本上与①号抗体相同，但效果不如①号。③单克隆小鼠抗 人细胞角蛋白，克隆为35BH11。该抗体的特点是：A，可检测几乎所有的非鳞状上皮包括卵巢腺癌，胃肠道腺癌，甲状腺癌，肝癌， 子宫癌，肾癌等。B、不与鳞状上皮起反应。C、对膀胱癌，鼻咽癌，胸腺癌等部分阳性。但是，该 抗体只能用于冰冻切片 ，涂片和细胞培养片。不能用于石蜡切片 。④单克隆小鼠抗 人细胞角蛋白，克隆34BE12。该 抗体属于高分子量类型，它可检测鳞状上皮管上皮和 复层上皮的组织及其来源的肿瘤。适用范围：可用于各种类型的切片 。作者：毕合生物公众号：毕合生物发布于 2023-03-24 14:05・IP 属地吉林生物化学​赞同​​添加评论​分享​喜欢​收藏​申请

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角蛋白 7（KRT7）基因 | MCE

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Gene

KRT7 - keratin 7 Gene

KRT7 - keratin 7 Gene

基因

蛋白

疾病

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直系同源

中文名称：角蛋白 7

种属: Homo sapiens

同用名: K7; CK7; SCL; K2C7

基因 ID: 3855

|

基因类型: protein coding

关于 KRT7

Cytogenetic location: 12q13.13

Genomic coordinates (GRCh38): 12:52,233,243-52,255,853 (from NCBI)

This gene has 13 transcripts (splice variants), 94 orthologues and 68 paralogues. Biased expression in thyroid (RPKM 146.2), placenta (RPKM 75.4) and 5 other tissues.

功能概要

该基因编码的蛋白质是角蛋白基因家族的一员。 II 型细胞角蛋白由碱性或中性蛋白组成，这些蛋白排列成对异型角蛋白链，在单层和复层上皮组织分化过程中共同表达。这种 II 型细胞角蛋白在内脏器官腔内衬的简单上皮细胞以及腺管和血管中特异性表达。编码 II 型细胞角蛋白的基因聚集在染色体 12q12-q13 区域。选择性剪接可能会导致多种转录本变异；然而，并非所有变体都得到了充分描述。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

KRT7 基因产物(1)

mRNA

Protein

Name

NM_005556.4

NP_005547.3

keratin, type II cytoskeletal 7

KRT7 蛋白结构

Filament

Filament: Intermediate filament protein (90 - 402)

0

100

200

300

400

469 a.a.

蛋白主名

其他名称

keratin, type II cytoskeletal 7

CK-7

关联疾病

疾病名称

别名

Pseudomyxoma Peritonei

Adenomucinosis

Gelatinous Ascites

Pmp

Mucinous Ascites

Syndrome Of Pseudomyxoma Peritonei

Bile Duct Adenoma

Cholangioadenoma

Adenoma Bile Duct

Adenoma, Bile Duct

Cystadenoma

Cystoma

Craniopharyngioma

Mucinous Cystadenocarcinoma

Cystadenocarcinoma, Mucinous

Pseudomucinous Cystadenocarcinoma

Cystadenocarcinoma Mucinous

Paget Disease, Extramammary

Extramammary Paget Disease

Cutaneous Paget'S Disease

Extramammary Paget'S Disease

Paget Disease Extramammary

Cutaneous Paget Disease

Paget'S Disease Of Skin

Empd

Extramammary Pagets Disease

Signet Ring Cell Adenocarcinoma

Signet Ring Cell Carcinoma

Carcinoma, Signet Ring Cell

Signet Ring Carcinoma

Carcinoma Signet Ring Cell

Adenosquamous Carcinoma

Adenosquamous Cell Carcinoma

Mixed Adenocarcinoma And Squamous Carcinoma

Carcinoma Adenosquamous

Carcinoma, Adenosquamous

Oncocytoma

Oxyphilic Adenoma

Follicular Adenoma, Oxyphilic Cell

Adenoma, Oxyphilic

Hurthle Cell Tumor

Oncocytic Neoplasm

Hidrocystoma

Apocrine Cystadenoma

Eccrine Hidrocystoma

Eccrine Cystadenoma

Eccrine Hidrocystoma Of Skin

Apocrine Adenoma

Appendix Cancer

Appendiceal Neoplasms

Cancer Of The Appendix

Malignant Neoplasm Of Appendix Vermiformis

Malignant Tumor Of Appendix

Malignant Tumor Of The Appendix

Malignant Neoplasm Of Appendix

Carcinoma Of The Appendix

Sertoli-Leydig Cell Tumor

Sertoli-Leydig Cell Tumors

Androblastoma Of Ovary

Arrhenoblastoma

Arrhenoblastoma Of Ovary

Sertoli-Leydig Cell Tumor Of The Ovary

Sertoli-Leydig Cell Tumor Of Intermediate Differentiation

Sertoli-Leydig Cell Tumor Of Ovary

Duodenum Cancer

Duodenal Cancer

Duodenal Neoplasms

Cancer Of Duodenum

Duodenal Neoplasm

Duodenal Carcinoma

Cancer, Duodenal

Malignant Neoplasm Of Duodenum

Cervical Adenocarcinoma

Adenocarcinoma Cervix Uteri

Adenocarcinoma Of Cervix

Adenocarcinoma Of The Uterine Cervix

Adenocarcinoma Of The Cervix Uteri

Mammary Paget'S Disease

Paget'S Disease

Mammary Paget Disease

Paget'S Disease Of The Breast

Paget Disease Of The Breast

Paget'S Disease Of The Nipple

Paget'S Disease, Mammary

Paget Cell Neoplasm

Paget Disease Of The Nipple

Pagets Disease Mammary

Osteitis Deformans

Secretory Meningioma

Meningioma

Thymic Carcinoma

Malignant Thymoma

Thymoma, Malignant

Pancreatic Ductal Carcinoma

Carcinoma, Pancreatic Ductal

Malignant Neoplasm Of Duct Of Wirsung

Pancreatic Duct Cancer

Carcinoma Pancreatic Ductal

Dysgerminoma

Sweat Gland Cancer

Sweat Gland Carcinoma

Malignant Neoplasm Of Sweat Gland

Malignant Tumor Of The Sweat Gland

Carcinoma Of The Sweat Gland

Primary Malignant Neoplasm Of Sweat Gland

Sweat Gland Neoplasms

Neuroendocrine Carcinoma

Neuroendocrine Cancer

Carcinoma Neuroendocrine

Carcinoma, Neuroendocrine

Benign Teratoma

Dermoid Cyst

Cystic Dermoid Choristoma

Dermoid Choristoma

Mature Cystic Teratoma

Dermoid Tumour

Teratoma, Benign

Dermoid Cyst Of Ovary

Epithelioid Sarcoma

Epithelioid Cell Sarcoma

Sarcoma Epithelioid

Sarcoma, Epithelioid

Trachea Carcinoma

Pancoast Tumor

Carcinoma Of The Trachea

Pancoast'S Tumor

Malignant Superior Sulcus Tumor

Malignant Superior Sulcus Tumour

Pancoast Tumour

Pancoast'S Syndrome

Pancoast'S Tumour

Pulmonary Sulcus Tumor

Pulmonary Sulcus Tumour

Superior Pulmonary Sulcus Syndrome

Pancoast Syndrome

Bladder Adenocarcinoma

Adenocarcinoma Of Bladder

Adenocarcinoma Of The Urinary Bladder

Bladder Adenocarcinoma, Not Otherwise Specified

Adenocarcinoma Bladder

Large Cell Carcinoma

Carcinoma, Large Cell

Carcinoma Large Cell

Carcinosarcoma

Mixed Tumor, Mullerian

Malignant Mixed Mesodermal Tumor

Malignant Mixed Mullerian Tumor

Mmmt

Mixed Tumor, Mesodermal

Mesodermal Mixed Tumor

Mixed Mesodermal Tumor

Mullerian Mixed Tumor

Mixed Mullerian Tumor

Malignant Mixed Müllerian Tumor

Mixed Müllerian Tumor

Mixed Tumor Mullerian

Mixed Tumor, Not Otherwise Specified

Bronchiolo-Alveolar Adenocarcinoma

Bronchioloalveolar Carcinoma

Bronchioalveolar Lung Carcinoma

Minimally Invasive Lung Adenocarcinoma

Carcinoma Bronchioloalveolar

Adenocarcinoma, Bronchiolo-Alveolar

Bronchioloalveolar Adenocarcinoma

Papillary Craniopharyngioma

Craniopharyngioma, Papillary

Papillary Rathke'S Pouch Tumor

Craniopharyngioma Papillary

Anal Canal Carcinoma

Anal Canal Cancer

Anal Canal And Perianal Gland Carcinoma

Carcinoma Of The Anal Canal

Carcinoma Of Anal Canal

Transitional Cell Carcinoma

Transitional Cell Neoplasm

Carcinoma, Transitional Cell

Transitional Carcinoma

Transitional Cell Tumor

Urothelial Cell Carcinoma

Carcinoma Transitional Cell

Transitional Cell Carcinoma Of Bladder

Ovarian Brenner Tumor

Benign Ovarian Brenner Tumor

Brenner Tumor

Benign Ovarian Brenner Tumour

Ovarian Brenner Tumour

Brenner Tumor Of Ovary

Benign Brenner Tumor

Thymus Cancer

Thymic Neoplasm

Thymic Tumor

Thymus Neoplasm

Thymus Neoplasms

Malignant Neoplasm Of Thymus

Neoplasm Of Thymus

Thymic Neoplasms

Thymoma, Familial

Thymic Carcinoma

Thymoma, Type C

Cancer Of Thymus

Malignant Tumour Of Thymus

Primary Malignant Neoplasm Of Thymus

Thymic Glandular Cancer

Thymus Gland Cancer

Acinar Cell Carcinoma

Acinic Cell Carcinoma

Acinic Cell Tumor

Carcinoma Acinar Cell

Carcinoma, Acinar Cell

Acinar Cell Tumor

Barrett Esophagus

Barrett'S Esophagus

Barrett Esophagus/Esophageal Adenocarcinoma

Barrett Metaplasia

Barrett'S Ulcer Of Esophagus

Ulcerative Esophagitis

Barrett'S Esophagus With Esophagitis

Barrett'S Oesophagus

Barretts Syndrome

Barrett Syndrome

BE

Peptic Ulcer Of Esophagus

Adenocarcinoma Of Esophagus

Bowen'S Disease

Bowens Disease

Papillary Carcinoma

Carcinoma, Papillary

Carcinoma Papillary

Ovarian Mucinous Neoplasm

Ovarian Mucinous Tumor

Malignant Ovarian Mucinous Neoplasm

Mucinous Tumor Of Ovary

Malignant Ovarian Mucinous Tumor

Papillary Adenocarcinoma

Infiltrating And Papillary Adenocarcinoma

Infiltrating Papillary Adenocarcinoma

Adenocarcinoma Papillary

Adenocarcinoma, Papillary

Brooke-Spiegler Syndrome

Cyld Cutaneous Syndrome

Spiegler-Brooke Syndrome

Familial Cylindromatosis

BRSS

Bss

Sbs

Multiple Familial Trichoepithelioma

Ancell-Spiegler Cylindromas

Familial Multiple Trichoepithelioma

Trichoepithelioma

Fc

Mft

Multiple Familial Trichoepitheliomas

Ccs

Turban Tumor Syndrome

Schilbach-Rott Syndrome

Eccrine Dermal Cylindroma

Familial Multiple Trichoepitheliomata

Vulva Adenocarcinoma

Adenocarcinoma Of The Vulva

Adenocarcinoma Of Vulva

Krukenberg Carcinoma

Krukenberg Tumor

Krukenberg Neoplasm

Krukenberg'S Tumor

Lymphoepithelioma-Like Carcinoma

Lymphoepithelial Carcinoma

Nasopharyngeal Type Undifferentiated Carcinoma

Ampulla Of Vater Cancer

Ampulla Of Vater Carcinoma

Ampullary Carcinoma

Malignant Tumour Of Ampulla Of Vater

Carcinoma Of Ampulla Of Vater

Carcinoma Of The Ampulla Of Vater

Ampulloma

Borst-Jadassohn Intraepidermal Carcinoma

Intraepidermal Epithelioma Of Jadassohn

Bowen'S Disease, Clonal

Vulval Paget'S Disease

Paget'S Disease Of Vulva

Vulval Paget Disease

Vulvar Paget'S Disease

Extramammary Paget Disease Of Vulva

Teratoma

Teratomas

Papillary Adenoma

Glandular Papilloma

Adenoma

Bile Duct Cancer

Bile Duct Carcinoma

Extrahepatic Bile Duct Carcinoma

Carcinoma Of Extrahepatic Bile Duct

Extrahepatic Bile Duct Cancer

Bile Duct Neoplasms

Bile Duct Tumor

Ca Extrahepatic Bile Ducts

Malignant Neoplasm Of The Extrahepatic Bile Duct

Bile Duct Extrahepatic Carcinoma

Malignant Tumor Of Extrahepatic Bile Duct

Sex Cord-Gonadal Stromal Tumor

Sex Cord-Gonadal Stromal Tumour

Sex Cord Stromal Tumour

Sex Cord-Stromal Neoplasm

Specialized Gonadal Neoplasm

Specialized Gonadal Tumor

Specialized Gonadal Tumour

Sex Cord-Gonadal Stromal Tumors

Sex Cord-Stromal Tumor

Malignant Testicular Sex Cord-Stromal Tumor

Sex Cord Stromal Tumor Of Testis

Anal Canal Adenocarcinoma

Adenocarcinoma Of The Anal Canal

Adenocarcinoma Of Anal Canal

Biliary Tract Benign Neoplasm

Extrahepatic Bile Duct Neoplasm

Neoplasm Of Extrahepatic Bile Ducts

Tumor Of The Extrahepatic Bile Duct

Intestinal Perforation

Perforation Of Intestine

Adenomatoid Tumor

Adenomatoid Tumour

Benign Localised Epithelial Mesothelioma

Benign Localized Epithelial Mesothelioma

Ceruminous Adenocarcinoma

Seminal Vesicle Adenocarcinoma

Gallbladder Adenocarcinoma

Adenocarcinoma Of The Gallbladder

Carcinoma Of The Gallbladder

Bladder Urachal Carcinoma

Urachal Cancer

Urachal Carcinoma

Urachus Cancer

Malignant Tumor Of Urachus

Ceruminoma

Ceruminous Adenoma

External Auditory Canal Ceruminous Adenoma

Cystitis Cystica

Cystadenocarcinoma

Necrotizing Sialometaplasia

Sialometaplasia, Necrotizing

Chordoma

CHDM

Notochordoma

Notochordal Sarcoma

Chordoma, Susceptibility To

Chordocarcinoma

Chordoepithelioma

Bladder Benign Neoplasm

Mucinous Adenocarcinoma

Mucin-Producing Adenocarcinoma

Mucin-Secreting Adenocarcinoma

Mucin-Secreting Carcinoma

Mucous Carcinoma

Pseudomyxoma Peritonei With Unknown Primary Site

Adenocarcinoma, Mucinous

Intrahepatic Bile Duct Adenoma

Adenoma Of Intrahepatic Bile Duct

Adenoma Of The Intrahepatic Bile Duct

Warthin Tumor

Papillary Cystadenoma Lymphomatosum

Adenolymphoma

Mucinous Ovarian Cystadenoma

Mucinous Cystadenoma Of Ovary

Ovarian Mucinous Cystadenoma

Nasal Cavity Cancer

Nasal Cavity Carcinoma

Malignant Neoplasm Of Nasal Cavities

Malignant Tumor Of The Nasal Cavity

Cancer Of Nasal Cavity

Carcinoma Of Nasal Cavity

Malignant Neoplasm Of Nasal Cavity

Neoplasm Of Nasal Cavity

Urinary Bladder Villous Adenoma

Villous Adenoma Of Urinary Bladder

Bladder Villous Adenoma

Eccrine Adenocarcinoma

Adenoid Basal Cell Carcinoma

Skin Adenoid Basal Cell Carcinoma

Basal Cell Carcinoma - Adenoid

Intestinal Obstruction

Inspissated Milk Syndrome

Milk Curd Syndrome

Appendix Disease

Disorder Of Appendix

Lung Benign Neoplasm

Lung Neoplasms

Tumor Of The Lung

Lung Tumor

Laryngeal Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma Of Larynx

Gallbladder Signet Ring Cell Adenocarcinoma

Signet Ring Cell Carcinoma Of The Gallbladder

Cystic Teratoma

Dermoid Cyst

Benign Teratoma

Benign Mesothelioma

Mesothelioma

Benign Tumor Of Mesothelium

Adenomatoid Tumor

Adenoid Cystic Carcinoma

Adenocystic Carcinoma

Cribriform Carcinoma

Cylindroma

Carcinoma Adenoid Cystic

Carcinoma, Adenoid Cystic

Adenoid Cystic Carcinoma Of Salivary Gland

Eccrine Dermal Cylindroma

Carcinoma, Cribriform

Pancreatic Serous Cystadenocarcinoma

Serous Cystadenocarcinoma Of Pancreas

Gastric Diffuse Adenocarcinoma

Diffuse Gastric Adenocarcinoma

Carcinoma, Diffuse Type

Sarcoma, Synovial

Synovial Sarcoma

Synovialosarcoma

Synovial Cell Sarcoma

Sarcoma Synovial

Ureter, Cancer Of

Ureter Carcinoma

Ureter Cancer

Ureteral Neoplasms

Malignant Neoplasm Of Ureter

Malignant Tumour Of Ureter

Malignant Ureteral Tumor

Ureteral Carcinoma

Ureteral Neoplasm

Merkel Cell Carcinoma

Trabecular Adenocarcinoma

Cutaneous Neuroendocrine Carcinoma

Trabecular Carcinoma

Carcinoma, Merkel Cell

Merkel Cell Cancer

Merkle Tumors

Mcc

Carcinoma Merkel Cell

Sweat Gland Disease

Sweat Gland Diseases

Salivary Gland Carcinoma

Salivary Gland Cancer

Malignant Neoplasm Of Salivary Gland

Salivary Gland Neoplasms

Leukoplakia Of Penis

Penile Leukoplakia

Balanitis Xerotica Obliterans

Kraurosis Of Penis

Scrotum Paget'S Disease

Paget'S Disease Of Scrotum

Scrotum Paget Disease

Paget Disease Of The Scrotum

Cervical Basaloid Squamous Cell Carcinoma

Cervical Basaloid Carcinoma

Ovarian Benign Neoplasm

Benign Ovarian Neoplasm

Renal Oncocytoma

Oncocytoma, Renal

Oncocytoma Of Kidney

Renal Epithelial Oncocytic Tumor

Oncocytoma Kidney

Oncocytoma Renal

Kidney Oncocytoma

Metanephric Adenoma

Adenoma

Acinar Cell Adenoma

Adenomas

Acinic Cell Adenoma

Renal Adenoma

Renal Cell Adenoma

Apocrine Sweat Gland Neoplasm

Apocrine Tumor

Apocrine Neoplasm

Endodermal Sinus Tumor

Yolk Sac Tumor

Endodermal Sinus Tumour

Hepatoid Yolk Sac Tumour

Infantile Embryonal Carcinoma

Yolk Sac Neoplasm

Yolk Sac Tumour

Eosinophilic Variant Of Chromophobe Renal Cell Carcinoma

Ureteral Benign Neoplasm

Neoplasm Of Ureter

Ureteral Tumor

Cancer Of The Ureter

Malignant Tumour Of Ureter

Ureteric Cancer

Primary Malignant Neoplasm Of Ureter

Small Intestine Cancer

Small Intestine Carcinoma

Cancer Of The Small Bowel

Small Bowel Cancer

Small Intestinal Carcinoma

Malignant Neoplasms Of The Small Intestine

Small Bowel Tumors

Malignant Tumor Of Small Intestine

Neoplasm Of Small Intestine

Urethral Diverticulum

Urethral Sacculation

Mesenchymal Chondrosarcoma

Chondrosarcoma, Mesenchymal

Chondrosarcoma Mesenchymal

Epithelial-Myoepithelial Carcinoma

Clear Cell Adenoma

Adenomyo-Epithelioma

Clear Cell Carcinoma

Emc

Epithelial Myoepithelial Carcinoma

Glycogen-Rich Adenocarcinoma

Glycogen-Rich Adenoma

Monomorphic Clear Cell Tumor

Tubular Solid Adenoma

Adenocarcinoma, Clear Cell

Anal Gland Adenocarcinoma

Adenocarcinoma Of Anal Ducts

Adenocarcinoma Of Anal Gland

Anal Glands Adenocarcinoma

Adenocarcinoma Of Anal Glands

Tubular Adenocarcinoma

Tubular Carcinoma

Adenocarcinoma Tubular

Adenocarcinoma, Tubular

Spindle Cell Sarcoma

Sarcoma

Sarcoma Spindle Cell

Sarcoma, Spindle Cell

Sarcoma - Category

Vulva Cancer

Vulvar Carcinoma

Malignant Neoplasm Of Vulva

Vulva Carcinoma

Carcinoma Of Vulva

Vulvar Cancer

Vulval Cancer

Vulvar Neoplasms

Ca Vulva

Malignant Tumor Of Vulva

Malignant Vulvar Tumor

Neoplasm Of Vulva

Vulval Neoplasm

Vulvar Neoplasm

Vulvar Tumor

Cancer Of Vulva

Malignant Tumour Of Vulva

Sertoli Cell Tumor

Tubular Androblastoma

Malignant Spiradenoma

Malignant Eccrine Spiradenoma

Eccrine Spiradenoma, Malignant

Mes

Kidney Benign Neoplasm

Renal And Ureteral Tumor

Benign Kidney Neoplasm

Sweat Gland Benign Neoplasm

Neoplasm Of Sweat Gland

Sweat Gland Tumor

Tumor Of The Sweat Gland

Sweat Gland Neoplasms

Sweat Gland Neoplasm

Mucoepidermoid Carcinoma

Mec

Salivary Gland Mucoepidermoid Carcinoma

C3772

Carcinoma Mucoepidermoid

Carcinoma, Mucoepidermoid

Linitis Plastica

Leather-Bottle Stomach

Hemosiderosis

Haemosiderosis

Iron Overload

Renal Cell Carcinoma, Nonpapillary

Renal Cell Carcinoma

RCC

Nonpapillary Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma

Hypernephroma

Adenocarcinoma Of Kidney

Renal Carcinoma, Chromophobe, Somatic

Clear Cell Carcinoma Of Kidney

Clear-Cell Metastatic Renal Cell Carcinoma

Clear Cell Renal Carcinoma

Renal Cell Carcinoma, Somatic

Conventional Renal Cell Carcinoma

Conventional Renal Cell Carcinoma

Renal Clear Cell Carcinoma

Ccrcc

Hereditary Clear Cell Renal Cell Carcinoma

Carcinoma, Renal Cell

Renal Cell Carcinoma, Clear Cell, Somatic

Renal Cell Carcinoma, Clear Cell

Clear Cell Kidney Carcinoma

Clear Cell Rcc

Cystic-Multilocular Variant

Clear Cell Renal Cell Adenocarcinoma

Hereditary Clear Cell Renal Cell Adenocarcinoma

Common Renal Cell Carcinoma

Crcc

Renal Cell Carcinoma Non-Papillary

Carcinoma Renal Cell

Renal Cell Cancer

Carcinoma, Renal Cell, Nonpapillary

Jejunal Adenocarcinoma

Glandular Cystitis

Cystitis Glandularis

Ovarian Mucinous Adenocarcinoma

Mucinous Carcinoma Of Ovary

Spiradenoma

Eccrine Spiradenoma

Benign Eccrine Spiradenoma

Eccrine Spiradenoma Of Skin

Es

Eccrine Spiradenoma, Benign

Adenocarcinoma

Adenocarcinomas

Adenoacanthoma Of Unspecified Site

Adenocarcinoid Of Unspecified Site

Adenocarcinoid Tumour Of Unspecified Site

Adenocarcinoma And Carcinoid Combined Of Unspecified Site

Adenocarcinoma Nos

Mucinous Bronchioloalveolar Adenocarcinoma

Bronchiolo-Alveolar Carcinoma, Mucinous

Appendix Adenocarcinoma

Cystadenocarcinoma

Mucinous Adenocarcinoma

Adenocarcinoma Of Appendix

Appendiceal Adenocarcinoma

Adenocarcinoma Of The Appendix

Colonic Type Adenocarcinoma

Nonmucinous Adenocarcinoma

Ovary Neuroendocrine Neoplasm

Neuroendocrine Tumor Of Ovary

Eyelid Carcinoma

Carcinoma Of The Eyelid

Mucinous Adenofibroma

Cholangiocarcinoma

Cholangiocarcinoma, Susceptibility To

Extrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma

Chlc

Chlc, Susceptibility To

Cc

Cholangiocarcinoma Of Biliary Tract

Cholangiocellular Carcinoma

Distal Cholangiocarcinoma

Perihilar Cholangiocarcinoma

Bile Duct Cancer

Cca

Adult Primary Cholangiocellular Carcinoma

Bile Duct Carcinoma

Eccrine Sweat Gland Cancer

Malignant Eccrine Skin Neoplasm

Malignant Eccrine Tumor

Urethral Villous Adenoma

Anus Adenocarcinoma

Adenocarcinoma Of Anus

Adenocarcinoma Of The Anus

Nephrogenic Adenoma

Nephrogenic Metaplasia

Papillary Cystadenocarcinoma

Cystadenocarcinoma, Papillary

Angiomyolipoma

Angiomyolipoma Of Kidney

Cholangiolocellular Carcinoma

Nephrogenic Adenoma Of Urinary Bladder

Nephrogenic Adenoma Of The Urinary Bladder

Basaloid Squamous Cell Carcinoma

Basaloid Carcinoma

Cystadenofibroma

Bartholin'S Gland Adenocarcinoma

Bartholin Gland Adenocarcinoma

Adenocarcinoma Of Bartholin'S Gland

Adenocarcinoma Of The Bartholin'S Gland

Pancreatic Foamy Gland Adenocarcinoma

Urethral Benign Neoplasm

Urethral Neoplasms

Neoplasm Of Urethra

Neoplasm. Urethra

Urethral Neoplasm

Urethral Carcinoma

Malignant Neoplasm Of Urethra

Anal Fistula

Anorectal Fistula

Rectal Fistula

Allingham Ulcer

Perianal Fistula

Fistula In Ano

Anorectum Fistula

Mixed Cell Type Cancer

Malignant Mixed Neoplasm

Malignant Mixed Tumor

Mixed Neoplasm

Mixed Tumor, Malignant

Malignant Mixed Cancer

Mixed Tumor

Malignant Mixed Tumor, Not Otherwise Specified

Mixed Salivary Gland Tumor

Mixed Tumor, Not Otherwise Specified

Nephrogenic Adenofibroma

Metanephric Adenofibroma

Mucinous Cystadenofibroma

Middle Ear Adenoma

Adenoma Of Middle Ear

Adenoma Of The Middle Ear

Auditory System Benign Neoplasm

Biliary Atresia

Congenital Biliary Atresia

Isolated Biliary Atresia

Isolated Atresia Of Bile Ducts

Non-Syndromic Biliary Atresia

Atresia Of Bile Duct

Biliary Atresia, Congenital

Atresia Of Bile Ducts

Bile Duct Atresia

Congenital Bile Duct Atresia

Ba - [Biliary Atresia]

Impervious Bile Duct

Atresia Of Common Duct

Biliary Duct Atresia

Bile Ductal Atresia

Cystic Duct Atresia

Hepatoblastoma

Syringocystadenoma Papilliferum

Fistulous Vegetative Verrucous Hydradenoma

Papillary Syringadenoma

Naevus Syringocystadenomatosus Papilliferus

Papillary Syringocystadenoma

Scap

Syringadenoma Papilliferum

Papillary Hidradenoma

Apocrine Adenoma

Tubular Apocrine Adenoma

Urethra Cancer

Cancer Of Urethra

Malignant Tumour Of Urethra

Malignant Urethral Neoplasm

Urethral Ca

Endometrial Transitional Cell Carcinoma

Chronic Cystitis

Breast Mucinous Carcinoma

Mucinous Carcinoma Of Breast

Invasive Mucinous Breast Carcinoma

Bile Duct Signet Ring Cell Carcinoma

Extrahepatic Bile Duct Signet Ring Cell Carcinoma

Bladder Signet Ring Cell Adenocarcinoma

Signet Ring Cell Adenocarcinoma Of Bladder

Urinary Bladder Signet Ring Adenocarcinoma

Craniopharyngioma

Neoplasm Of Rathke'S Pouch

Adamantinomatous Tumor

Craniopharyngeal Duct Tumor

Dysodontogenic Epithelial Tumor

Rathke'S Pouch Tumor

Ovarian Seromucinous Carcinoma

Mixed Epithelial Carcinoma Of Ovary

Ovary Mixed Epithelial Carcinoma

Fibroma

Pancreatic Serous Cystic Neoplasm

Pancreatic Serous Neoplasm

Endosalpingiosis

Endometrial Cancer

Endometrial Carcinoma

Endometrial Neoplasm

Malignant Neoplasm Of Endometrium

Endometrioid Carcinoma

Endometrial Neoplasms

Carcinoma, Endometrioid

Endometrial Cancer, Familial

Endometrial Carcinoma, Somatic

Endometrial Cancer, Susceptibility To

Endometrial Ca

Malignant Endometrial Neoplasm

Neoplasm Of Endometrium

Primary Malignant Neoplasm Of Endometrium

Tumor Of Endometrium

Carcinoma Of The Endometrium

Endometrioid Carcinoma Of Female Reproductive System

ENDMC

Carcinoma Endometrioid

Endometrial Cancers

Cancer, Endometrial

Uterine Corpus Cancer

Hepatoid Adenocarcinoma

Epididymis Adenocarcinoma

Adenocarcinoma Of The Epididymis

Epididymis Cancer

Malignant Tumor Of Epididymis

Malignant Epididymal Tumor

Malignant Neoplasm Of Epididymis

Neoplasm Of Epididymis

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Cervical Mucinous Adenocarcinoma

Adenosquamous Gallbladder Carcinoma

Adenosquamous Carcinoma Of Gallbladder

Adenosquamous Carcinoma Of The Gallbladder

Gallbladder Adenosquamous Carcinoma

Sarcomatoid Renal Cell Carcinoma

Renal Cell Carcinoma, Spindle Cell

Papillary Transitional Carcinoma

Papillary Transitional Cell Carcinoma

Anus Basaloid Carcinoma

Basaloid Carcinoma Of The Anus

Anal Basaloid Carcinoma

Gallbladder Cancer

Gallbladder Carcinoma

Gallbladder Neoplasm

Malignant Neoplasm Of Gallbladder

Malignant Tumour Of Gallbladder

Gallbladder Ca

Localized Malignant Gallbladder Neoplasm

Malignant Tumor Of The Gallbladder

Tumor Of The Gallbladder

Cancer Of The Gallbladder

Carcinoma Gallbladder

Carcinoma Of Gallbladder

Gallbladder Neoplasms

Malignant Neoplasm Of Gallbladder Localized

Cancer Of Gallbladder

Primary Malignant Neoplasm Of Gallbladder

Lacrimal Gland Carcinoma

Lacrimal Gland Cancer

Carcinoma Of The Lacrimal Gland

Malignant Neoplasm Of Lacrimal Gland

Malignant Tumour Of Lacrimal Gland

Neoplasm Of Lacrimal Gland

Tumor Of The Lacrimal Gland

Malignant Tumor Of Lacrimal Gland

Sigmoid Neoplasm

Sigmoid Neoplasms

Neoplasm Of Sigmoid Colon

Tumor Of Sigmoid Colon

Inverted Transitional Papilloma

Transitional Papilloma, Inverted

Transitional Cell Papilloma, Inverted

Myoepithelial Carcinoma

Malignant Myoepithelioma

Myoepithelioma Carcinoma

Adenoid Squamous Cell Carcinoma

Acantholytic Squamous Cell Carcinoma

Adenocarcinoma With Squamous Metaplasia

Adenoacanthoma

Pseudoglandular Squamous Carcinoma

Ovarian Endodermal Sinus Tumor

Endodermal Sinus Tumor Of Ovary

Ovarian Yolk Sac Tumor

Endodermal Sinus Tumour Of Ovary

Ovarian Endodermal Sinus Tumour

Ovarian Yolk Sac Tumour

Renal Pelvis Adenocarcinoma

Adenocarcinoma Of Renal Pelvis

Adenocarcinoma Of The Kidney Pelvis

Ovarian Mucinous Adenofibroma

Ovarian Mucinous Cystadenofibroma

Rete Testis Neoplasm

Rete Testis Adenocarcinoma

Adenocarcinoma Of Rete Testis

Adenocarcinoma Of The Rete Testis

Urethra Adenocarcinoma

Adenocarcinoma Of The Urethra

Urethral Adenocarcinoma

Breast Papillary Carcinoma

Breast Solid Papillary Carcinoma

Papillary Carcinoma Of Breast

Papillary Carcinoma Of The Breast

Solid Papillary Carcinoma Of The Breast

Urethra Clear Cell Adenocarcinoma

Clear Cell Adenocarcinoma Of The Urethra

Urethral Clear Cell Adenocarcinoma

Chromophil Adenoma Of The Kidney

Papillary Adenoma Of The Kidney

Breast Hemangiopericytoma

Hemangiopericytoma Of The Breast

Ampulla Of Vater Adenocarcinoma

Adenocarcinoma Of Ampulla Of Vater

Ampullary Adenocarcinoma

Malignant Peripheral Nerve Sheath Tumor

Mpnst

Malignant Neurilemmoma

Neurofibrosarcoma

Malignant Neurofibroma

Malignant Schwannoma

Neurogenic Sarcoma

Schwannoma, Malignant

Malignant Neoplasm Of The Peripheral Nerve Sheath

Malignant Peripheral Nerve Sheath Tumors

Pleomorphic Carcinoma

Oncocytic Breast Carcinoma

Appendiceal Neoplasm

Appendix Neoplasm

Neoplasm Of Appendix

Appendiceal Neoplasms

Appendiceal Cancer

Appendix Cancer

Malignant Neoplasm Of Appendix Vermiformis

Malignant Tumour Of Appendix

Cystitis

Infective Cystitis

Urocystitis

Pyocystitis

Sensory Organ Benign Neoplasm

Sebaceous Adenocarcinoma

Sebaceous Carcinoma

Adenocarcinoma Of The Sebaceous Gland

Malignant Neoplasm Of Sebaceous Gland

Malignant Sebaceous Tumor

Adenocarcinoma, Sebaceous

Malignant Sebaceous Neoplasm

Sebaceous Gland Neoplasms

Large Cell Neuroendocrine Carcinoma

Mesothelioma, Malignant

Malignant Mesothelioma

Pleural Mesothelioma

MESOM

Mesothelioma, Somatic

Advanced Malignant Mesothelioma

Asbestos-Related Malignant Mesothelioma

Diffuse Malignant Mesothelioma

Malignant Tumor Of Mesothelium

Malignant Mesothelioma, Susceptibility To

Mesothelioma Diffuse Malignant

Mesothelioma

Malignant Pleural Mesothelioma

Clear Cell Basal Cell Carcinoma

Skin Clear Cell Basal Cell Carcinoma

Aortic Malignant Tumor

Aortic Malignant Neoplasm

Malignant Aortic Neoplasm

Apocrine Adenocarcinoma

Apocrine Carcinoma

Apocrine Gland Carcinoma

Carcinoma Of The Apocrine Gland

Carcinoma Of Apocrine Gland

Transitional Papilloma

Transitional Cell Papilloma

Transitional Cell Papilloma, Benign

Fibrolamellar Carcinoma

Fibrolamellar Hepatocellular Carcinoma

Fhcc

Fibrolamellar Hepatocarcinoma

Hepatocellular Carcinoma, Fibrolamellar

Oncocytic Hepatocellular Tumor

Eosinophilic Glassy Cell Hepatoma

Eosinophilic Hepatocellular Carcinoma With Lamellar Fibrosis

Fl-Hcc

Fibrolamellar Oncocytic Hepatoma

Hepatocellular Carcinoma With Increased Stromal Fibrosis

Polygonal Cell Hepatocellular Carcinoma With Fibrous Stroma

Gastric Signet Ring Cell Adenocarcinoma

Signet Ring Cell Gastric Adenocarcinoma

Signet Ring Cell Adenocarcinoma Of The Stomach

Male Urethral Cancer

Male Urethral Malignant Neoplasm

Ureter Squamous Cell Carcinoma

Ureteral Epidermoid Carcinoma

Ovarian Primitive Germ Cell Tumor

Ureter Adenocarcinoma

Adenocarcinoma Of Ureter

Ureteral Adenocarcinoma

Nodular Hidradenoma

Eccrine Nodular Hidradenoma

Eccrine Acrospiroma

Benign Breast Adenomyoepithelioma

Benign Adenomyoepithelioma Of The Breast

Ovarian Germ Cell Teratoma

Germ Cell Teratoma Of Ovary

Ovarian Teratoma

Meibomian Cyst

Chalazion

Meibomian Gland Lipogranuloma

Tarsal Cyst

Mucinous Intrahepatic Cholangiocarcinoma

Mucin-Producing Intrahepatic Cholangiocarcinoma

Lung Clear Cell Carcinoma

Epithelial Predominant Wilms' Tumor

Epithelial Predominant Kidney Adenosarcoma

Epithelial Predominant Renal Wilms Tumor

Epithelial Predominant Renal Wilms Tumour

Epithelial Predominant Wilms' Tumour

Sinonasal Undifferentiated Carcinoma

Highly Aggressive Undifferentiated Carcinoma Of The Nasal Cavity And Paranasal Sinuses

Snuc

Rete Testis Adenoma

Jejunal Cancer

Jejunal Neoplasms

Malignant Neoplasm Of Jejunum

Malignant Tumor Of Jejunum

Fallopian Tube Carcinoma

Fallopian Tube Cancer

Cancer Of The Fallopian Tube

Carcinoma Of Fallopian Tube

Neoplasm Of Fallopian Tube

Fallopian Tube Neoplasms

Fallopian Tube Ca

Fallopian Tube Neoplasm

Malignant Neoplasm Of Uterine Tube

Malignant Tumor Of Fallopian Tube

Malignant Tumour Of Fallopian Tube

Tumor Of The Fallopian Tube

Tumor, Fallopian Tube, Malignant

Malignant Tumor Of Fallopian Tubes

Cancer Of Fallopian Tubes

Malignant Tubal Tumor

Tubal Cancer

Malignant Neoplasm Of Fallopian Tube

Primary Malignant Neoplasm Of Fallopian Tube

Cancer Of The Oviduct

Rectum Squamous Cell Carcinoma

Squamous Cell Carcinoma Of The Rectum

Rectal Squamous Cell Carcinoma

Squamous Carcinoma Of Rectum

Breast Ductal Carcinoma

Ductal Breast Carcinoma

Duct Carcinoma

Carcinoma, Ductal

Mammary Ductal Carcinoma

Ductal Carcinoma

Malignant Syringoma

Microcystic Adnexal Carcinoma

Microcystic Adnexal Carcinoma Of Skin

Syringomatous Carcinoma

Eccrine Epithelioma

Gastric Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Stomach

Squamous Cell Carcinoma Of The Stomach

Epithelioid Type Angiomyolipoma

Epithelioid Angiomyolipoma

Endometrial Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Endometrium

Lung Giant Cell Carcinoma

Carcinoma, Giant Cell

Giant Cell Carcinoma

Giant Cell Lung Carcinoma

Carcinoma Giant Cell

Giant Cell Carcinoma Of Lung

Central Nervous System Fibrosarcoma

Fibrosarcoma Of The Cns

Clear Cell Hidradenoma

Clear Cell Myoepithelioma

Eccrine Acrospiroma

Bladder Clear Cell Adenocarcinoma

Bladder Mesonephric Adenocarcinoma

Clear Cell Adenocarcinoma Of Bladder

Nasal Cavity Adenocarcinoma

Adenocarcinoma Of Nasal Cavity

Adenocarcinoma Of The Nasal Cavity

Periampullary Adenocarcinoma

Anal Paget'S Disease

Anal Paget Disease

Paget'S Disease Of Anus

Paget'S Disease Of The Anus

Paget Disease Of The Anus

Corneal Dystrophy, Posterior Polymorphous, 4

PPCD4

Posterior Polymorphous Corneal Dystrophy 4

Balloon Cell Malignant Melanoma

Keratinizing Squamous Cell Carcinoma

Squamous Cell Carcinoma, Keratinizing

Keratinizing Epidermoid Carcinoma

Cribriform Carcinoma

Ductal Carcinoma, Cribriform Type

Carcinoma Cribriform

Carcinoma, Cribriform

Wolffian Duct Adenoma

Benign Mesonephroma

Mesonephric Adenoma

Mesonephroma, Benign

Fatwo

Female Adnexal Tumor Of Probable Wolffian Origin

Wat

Wolffian Adenoma

Wolffian Adnexal Tumor

Wolffian Tumor

Small Cell Cancer Of The Lung

Small Cell Lung Cancer

Small Cell Lung Carcinoma

Sclc

Small-Cell Cancer Of Lung

Lung Small Cell Carcinoma

Sclc1

Sccl

Cancer, Lung, Small Cell

Small Cell Carcinoma Of Lung

Carcinoma, Small Cell

Duodenum Disease

Duodenal Diseases

Duodenal Disease

Duodenum Disorder

Tonsil Cancer

Tonsillar Neoplasms

Malignant Neoplasm Of Faucial Tonsil

Malignant Neoplasm Of Palatine Tonsil

Malignant Neoplasm Of Tonsil, Faucial

Malignant Tonsillar Tumor

Malignant Tumor Of Tonsil

Tonsillar Carcinoma

Malignant Neoplasm Tonsil

Lung Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma Of Lung

Pulmonary Adenoid Cystic Carcinoma

Lung Large Cell Carcinoma

Large Cell Carcinoma Of Lung

Large Cell Lung Carcinoma

Large Cell Lung Cancer

Aggressive Digital Papillary Adenocarcinoma

Salivary Gland Disease

Salivary Gland Disorders

Salivary Gland Diseases

Non-Neoplastic Salivary Gland Disease

Non-Neoplastic Salivary Gland Disorder

Disorder Of Salivary Gland

Lesion Of Salivary Gland Nos

Pericardium Cancer

Malignant Neoplasm Of Pericardium

Malignant Tumor Of Pericardium

Pericardial Tumor

Neoplasm Of Pericardium

Hemangioma

Hemangiomas

Eccrine Porocarcinoma

Porocarcinoma

Eccrine Porocarcinoma Of Skin

Malignant Eccrine Poroma

Papilloma

Papillomatosis

Hidradenoma

Adenoma, Sweat Gland

Hidradenoma Of Skin

Sweat Gland Adenoma

Syringoadenoma

Eccrine Acrospiroma

Benign Neoplasm Of Sweat Gland

Paraganglioma

Chemodectoma

Glomus Body Tumor

Paragangliomas

Carotid Body Paraganglioma

Extra-Adrenal Paraganglioma

Bartholin'S Gland Carcinoma

Bartholin Gland Carcinoma

Carcinoma Of Bartholin'S Gland

Bartholin'S Gland Disease

Bartholin Gland Disease

Malignant Acrospiroma

Eccrine Ductal Carcinoma

Hidradenocarcinoma

Anaplastic Syringoma

Eccrine Ductal Carcinoma Of Skin

Clear Cell Eccrine Carcinoma

Malignant Clear Cell Acrospiroma

Malignant Nodular/Clear Cell Hidradenoma

Primary Mucoepidermoid Cutaneous Carcinoma

Sweat Gland Adenocarcinoma

Squamous Cell Carcinoma

Epidermoid Carcinoma

Squamous Cell Cancer

Carcinoma, Squamous Cell

Squamous Cell Skin Cancer

Malignant Squamous Cell Tumor

Squamous Carcinoma

Squamous Cell Epithelioma

Carcinoma Squamous Cell

Neoplasms, Squamous Cell

Squamous Cell Carcinoma - Category

Malignant Squamous Cell Neoplasm

Squamous Cell Carcinoma Of Skin

Polycystic Liver Disease 1 With Or Without Kidney Cysts

Polycystic Liver Disease 1

PCLD1

Cyst

Liver Disease, Polycystic, Type 1

Polycystic Liver Disease

Ovarian Germ Cell Cancer

Ovarian Germ Cell Tumor

Malignant Germ Cell Tumor Of Ovary

Germ Cell Neoplasm Of Ovary

Germ Cell Tumor Of Ovary

Mogct

Malignant Ovarian Germ Cell Tumor

Malignant Ovarian Germ Cell Neoplasm

Breast Myoepithelial Neoplasm

Breast Myoepithelial Tumor

Malignant Breast Myoepithelioma

Breast Adenomyoepithelioma

Adenomyoepithelioma Of The Breast

Breast Adenomyoepithelioma With Malignant Change

Malignant Adenomyoepithelioma Of Breast

Renal Pelvis Transitional Cell Carcinoma

Urothelial Cell Carcinoma Of Renal Pelvis

Renal Pelvis Urothelial Carcinoma

Transitional Cell Carcinoma Of Renal Pelvis

Vulvar Sebaceous Carcinoma

Adenomyoma

Lymphangitis

Inflammation Of Lymphatics

Squamous Cell Papilloma

Papilloma

Epidermoid Papilloma

Papilloma, Squamous Cell

Clear Cell Adenocarcinoma

Mesonephroma

Water-Clear Cell Adenocarcinoma

Adenocarcinoma, Clear Cell

Malignant Mesonephroma

Mesonephroid Clear Cell Carcinoma

Mesonephroma, Malignant

Water-Clear Cell Carcinoma

Wolffian Duct Neoplasm

Adenocarcinoma Clear Cell

Mesonephric Tumor

Paranasal Sinus Cancer

Paranasal Sinus Adenoid Cystic Carcinoma

Paranasal Sinus Mucoepidermoid Carcinoma

Paranasal Sinus Squamous Cell Carcinoma

Paranasal Sinus Neoplasms

Adenoid Cystic Carcinoma Of Accessory Sinus

Adenoid Cystic Carcinoma Of Paranasal Sinus

Epidermoid Carcinoma Of The Paranasal Sinus

Mucoepidermoid Carcinoma Of Accessory Sinus

Paranasal Sinus Adenocarcinoma

Squamous Cell Carcinoma Of Paranasal Sinus

Paranasal Sinus Neoplasm

Adenocarcinoma Of Accessory Sinus

Breast Leiomyosarcoma

Leiomyosarcoma Of The Breast

Epididymal Neoplasm

Neoplasm Of Epididymis

Adenofibroma

Malignant Epithelial Mesothelioma

Epithelioid Mesothelioma, Malignant

Breast Mucoepidermoid Carcinoma

Mucoepidermoid Carcinoma Of Breast

Mucoepidermoid Carcinoma Of The Breast

Malignant Biphasic Mesothelioma

Mesothelioma, Biphasic, Malignant

Mixed Mesothelioma

Klatskin'S Tumor

Klatskin Tumor

Hilar Cholangiocarcinoma

Perihilar Cholangiocarcinoma

Hilar Cholangiocellular Carcinoma

Klatskin Tumour

Klatskin'S Tumour

Perihilar Extrahepatic Bile Duct Carcinoma

Hilar Cca

Adenocarcinoma Of Hepatic Duct

Klatskin Tumour Of Biliary Tree

Internal Hemorrhoid

Internal Hemorrhoids

Thymoma

Primary Thymic Epithelial Neoplasm

Primary Thymic Epithelial Tumor

Thymus Neoplasms

Pericardial Mesothelioma

Malignant Mesothelioma Of Pericardium

Malignant Pericardial Mesothelioma

Epithelioid Trophoblastic Tumor

Trophoblastic Tumor, Epithelioid

Peritoneum Cancer

Peritoneal Neoplasm

Cancer Of Peritoneum

Malignant Tumor Of Peritoneum

Peritoneal Neoplasms

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Ovarian Mesodermal Adenosarcoma

Ovarian Mullerian Adenosarcoma

Ovarian Adenosarcoma

Cutaneous Mucoepidermoid Carcinoma

Mucoepidermoid Carcinoma Of Skin

Mucoepidermoid Skin Carcinoma

Skin Carcinoma

Skin Cancer

Carcinoma Of Skin

Ca - Skin Cancer

Cancer Of Skin

Malignant Neoplasm Of Skin

Melanoma And Non-Melanoma Skin Cancer

Skin Cancers

Cancer, Skin

Parachordoma

Erysipeloid

Infection Due To Erysipelothrix Rhusiopathiae

Erysipelothrix Infection

Breast Metaplastic Carcinoma

Metaplastic Carcinoma Of The Breast

Metaplastic Breast Carcinoma

Metaplastic Carcinoma Of Breast

Metaplastic Breast Cancer

Vulvar Disease

Vulvar Diseases

Vulvar Disorders

Syringoma

Syringomas

Eccrine Sweat Gland Neoplasm

Eccrine Skin Neoplasm

Eccrine Tumor

Eccrine Neoplasm

Malignant Eccrine Neoplasm

Biliary Papillomatosis

Bile Duct Papillomatosis

Collecting Duct Carcinoma

Kidney Medullary Carcinoma

Renal Medullary Carcinoma

Bdc

Bellini Carcinoma

Bellini Duct Carcinoma

Cdc

Collecting Duct Carcinoma Of The Kidney

Renal Cell Adenocarcinoma

Carcinoma Of Renal Collecting Duct

Renal Carcinoma, Collecting Duct Type

Renal Cell Carcinoma

Bellini'S Duct Carcinoma

Renal Collecting Duct Carcinoma

Adenocarcinoma Of Kidney

Atrophic Vulva

Atrophy Of Vulva

Papillary Serous Adenocarcinoma

Micropapillary Serous Carcinoma

Serous Surface Papillary Carcinoma

Papillary Serous Carcinoma

Papillary Serous Cystadenocarcinoma

Cervical Clear Cell Adenocarcinoma

Clear Cell Carcinoma Of The Cervix Uteri

Bronchus Cancer

Malignant Neoplasm Of Bronchus And Lung

Bronchus Carcinoma

Bronchogenic Carcinoma

Malignant Neoplasm Of Bronchus Or Lung

Bc - Bronchogenic Carcinoma

Carcinoma, Bronchogenic

Bronchial Neoplasms

Blastoma

Embryoma

Salivary Gland Adenoid Cystic Carcinoma

Cylindroma

Anal Canal Paget'S Disease

Anal Canal Paget Disease

Paget'S Disease Of Anal Canal

Paget'S Disease Of The Anal Canal

Paget Disease Of The Anal Canal

Bile Duct Mucoepidermoid Carcinoma

Mucoepidermoid Carcinoma Of The Bile Duct

Extrahepatic Bile Duct Mucoepidermoid Carcinoma

Esophageal Adenosquamous Carcinoma

Cerebrovascular Benign Neoplasm

Female Urethral Cancer

Female Urethral Malignant Neoplasm

Intraductal Breast Benign Neoplasm

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Ascending Colon Cancer

Malignant Tumor Of Ascending Colon

Ca Ascending Colon

Malignant Neoplasm Of Right Colon

Malignant Neoplasm Of Ascending Colon

Struma Ovarii

Intratubular Embryonal Carcinoma

Stage 0 Testicular Embryonal Carcinoma

Choriocarcinoma Of The Testis

Testicular Choriocarcinoma

Villous Adenoma

Adenoma Villous

Adenoma, Villous

Duodenum Adenocarcinoma

Duodenal Adenocarcinoma

Adenosquamous Bile Duct Carcinoma

Bile Duct Adenosquamous Carcinoma

Mature Teratoma

Dermoid Cyst

Benign Teratoma

Intrahepatic Cholangiocarcinoma

Cholangiocarcinoma

Intrahepatic Bile Duct Carcinoma

Peripheral Cholangiocarcinoma

Peripheral Intrahepatic Cholangiocarcinoma

Adenocarcinoma Of Intra-Hepatic Bile Ducts

Cholangiocarcinoma, Unspecified Site

Cholangiocarcinoma Of Liver

Biphasic Synovial Sarcoma

Synovial Sarcoma, Biphasic

Biphasic Sarcoma Of Synovium

Adenocarcinoma In Situ

Breast Lobular Carcinoma

Cancer, Breast, Lobular

Lobular Breast Carcinoma

Bile Duct Cysts

Choledochal Cyst

Choledochal Cysts

Choledochocele

Biliary Cyst

Congenital Choledochal Cyst

Bile Duct Cyst

Congenital Cystic Dilatation Of The Biliary Tract

Congenital Bile Duct Dilatation

Xanthogranulomatous Pyelonephritis

Pyelonephritis, Xanthogranulomatous

Prostatic Urethral Cancer

Bilateral Hypoactive Labyrinth

Hypoactive Bilateral Labyrinthine Dysfunction

Hypoactive Labyrinth, Bilateral

Eccrine Acrospiroma

Acrospiroma

Poroma

Eccrine Hidradenoma

Eccrine Hidradenoma Of Skin

Hidradenoma

Adenoma, Sweat Gland

Benign Neoplasm Of Sweat Gland

Eccrine Poroma

Chromophobe Renal Cell Carcinoma

Chromophobe Adenocarcinoma

Chromophobe Carcinoma Of Kidney

Kidney Chromophobe

Renal Cell Carcinoma, Chromophobe Cell

Crcc

Chrcc

Chromophobe Renal Cell Adenocarcinoma

Chromophobe Renal Carcinoma

Chromophobe Carcinoma

Rectum Neuroendocrine Neoplasm

Neuroendocrine Tumor Of Rectum

Neuroendocrine Tumor Of The Rectum

Net Of The Rectum

Rectal Net

Rectal Neuroendocrine Tumor

Rectal Neuroendocrine Neoplasm

Breast Secretory Carcinoma

Secretory Breast Carcinoma

Juvenile Breast Carcinoma

Juvenile Carcinoma Of The Breast

Juvenile Secretory Carcinoma Of Breast

Juvenile Breast Cancer

Sbc

Secretory Carcinoma Of The Breast

Tinea Cruris

Dermatophytosis Of Groin & Perianal Area

Dermatophytosis Of Groin And Perianal Area

Dhobie Itch

Tinea Of Perianal Region

Jejunal Neoplasm

Jejunal Tumor

Neoplasm Of Jejunum

Tumor Of Jejunum

Ovarian Cystadenoma

Cystoma Serosum Simplex

Simple Cystoma Of Ovary

Simple Cystoma Of The Ovary

Anus Disease

Anal Fissure

Ulcer Of Anus

Anus Diseases

Anal Disease

Anal Fissure And Fistula

Anal Ulcer

Fissure In Ano

Nontraumatic Tear Of Anus

Solitary Anal Ulcer

Abnormality Of The Anus

Anal Disorders

Ulcer Of Anus And Rectum

Solitary Ulcer Of Anus

Stercoral Ulcer Of Anus

Primary Biliary Cholangitis

Primary Biliary Cirrhosis

Biliary Liver Cirrhosis

Chronic Nonsuppurative Destructive Cholangitis

Familial Primary Biliary Cirrhosis

Pbc

Hanot Syndrome

Cholestatic Cirrhosis

Biliary Cirrhosis Primary

Liver Cirrhosis, Biliary

Hanot'S Cirrhosis

Biliary Cirrhosis

Pericholangiolic Biliary Cirrhosis

Tannhauser-Magendantz Syndrome

Hanot-Rossle Syndrome

Hypertrophic Cirrhosis

Todd Cirrhosis

Hanot Cirrhosis

Charcot Cirrhosis

Mahon-Tannhauser Syndrome

Toxic Cirrhosis

Hypertrophic Biliary Cirrhosis

Monolobular Cirrhosis

Unilobar Cirrhosis

Xanthomatous Biliary Cirrhosis

Middle Ear Adenocarcinoma

Adenocarcinoma Of Middle Ear

Adenocarcinoma Of The Middle Ear

Lung Sarcomatoid Carcinoma

Sarcomatoid Carcinoma Of The Lung

Pulmonary Sarcomatoid Carcinoma

Solid Adenocarcinoma With Mucin Production

Bile Duct Cystadenocarcinoma

Biliary Cystadenocarcinoma

Intrahepatic Bile Duct Cystadenocarcinoma

Intrahepatic Bile Duct Mucinous Cystic Neoplasm With An Associated Invasive Carcinoma

Vaginal Tubulovillous Adenoma

Mediastinal Cancer

Mediastinal Neoplasms

Mediastinal Tumor

Mediastinum Cancer

Neoplasm Of Mediastinum

Tumour Of Mediastinum

Malignant Tumor Of Mediastinum

Intraductal Papilloma

Papilloma, Intraductal

Ductal Papilloma

Papilloma Intraductal

Lung Cancer Susceptibility 3

Lung Adenocarcinoma

Adenocarcinoma Of Lung

LNCR3

Adenocarcinoma Of Lung, Susceptibility To

Bronchogenic Lung Adenocarcinoma

Nonsmall Cell Adenocarcinoma

Adenocarcinoma Lung

Lung Adenocarcinomas

Non-Small Cell Adenocarcinoma

Pancreatic Cancer

Pancreatic Carcinoma

Carcinoma Of Pancreas

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Cancer Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Peritoneal Mesothelioma

Malignant Mesothelioma Of Peritoneum

Advanced Malignant Mesothelioma Of Peritoneum

Advanced Malignant Peritoneal Mesothelioma

Advanced Peritoneal Malignant Mesothelioma

Anal Squamous Cell Carcinoma

Epidermoid Anal Carcinoma

Carcinoma Of Anal Margin

Epulis

Epulides

Gingival Polyp

Polyp Of Gum

Papilloma Of Choroid Plexus

Choroid Plexus Papilloma

CPP

Childhood Choroid Plexus Papilloma

Papilloma Choroid Plexus

Papilloma, Choroid Plexus

Choroid Plexus Carcinoma

Main Bronchus Cancer

Malignant Neoplasm Of Main Bronchus

Ca Main Bronchus

Oropharynx Cancer

Oropharyngeal Cancer

Oropharyngeal Carcinoma

Malignant Neoplasm Of Oropharynx

Malignant Oropharyngeal Tumor

Malignant Tumor Of Oropharynx

Malignant Tumour Of Mesopharynx

Oropharyngeal Cancer, Adult

Cancer Of The Oropharynx

Medullary Colon Carcinoma

Mixed Germ Cell Cancer

Mixed Germ Cell Tumor

Mixed Germ Cell Neoplasm

Mixed Germ Cell Tumour

Mixed Teratoma And Seminoma

Small Cell Carcinoma

Small Cell Carcinoma, Intermediate Cell

Intermediate Cell Small Cell Carcinoma

Small Cell Carcinoma - Intermediate Cell

Small Cell Carcinoma Of Lung

Carcinoma, Small Cell

Prostate Neuroendocrine Neoplasm

Neuroendocrine Tumor Of The Prostate

Bladder Transitional Cell Papilloma

Bladder Papilloma

Transitional Cell Papilloma Of Bladder

Urinary Bladder Urothelial Papilloma

Urothelial Papilloma

Bladder Urothelial Papilloma

Endocervical Carcinoma

Carcinoma Of Endocervix

Carcinoma Of The Endocervix

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Kidney Cortex Disease

Bladder Papillary Transitional Cell Neoplasm

Urinary Bladder Papillary Urothelial Neoplasm

Bladder Papillary Urothelial Neoplasm

Urinary Tract Papillary Transitional Cell Benign Neoplasm

Inverted Papilloma Of Urinary Tract

Papillary Transitional Cell Neoplasm Of The Urinary Tract

Urinary Tract Inverted Papilloma

Inverted Urothelial Papilloma

Ovary Adenocarcinoma

Ovarian Adenocarcinoma

Adenocarcinoma Of The Ovary

Ovarian Adenoacanthoma

Adenocarcinoma Of Ovary

Subareolar Duct Papillomatosis

Adenoma Of The Nipple

Nipple Benign Neoplasm

Tumor Of Nipple

Breast Adenocarcinoma

Mammary Adenocarcinoma

Adenocarcinoma Of Breast

Serous Cystadenocarcinoma

Serous Adenocarcinoma

Cystadenocarcinoma, Serous

Serous Carcinoma

Cystadenocarcinoma Serous

Thyroid Gland Hurthle Cell Carcinoma

Oncocytic Carcinoma Of The Thyroid

Thyroid Cancer, Hurthle Cell

Thyroid Gland Cancer

Thyroid Gland Carcinoma

Malignant Neoplasm Of Thyroid Gland

Malignant Tumour Of Thyroid Gland

Thyroid Neoplasm

Thyroid Neoplasms

Neoplasm Of Thyroid Gland

Thyroid Gland Neoplasm

Head And Neck Cancer, Thyroid

Neoplasm Of The Thyroid Gland

Cancer Of The Thyroid

Primary Malignant Neoplasm Of Thyroglossal Duct

Malignant Neoplasm Of Thyroglossal Duct

Primary Malignant Neoplasm Of Thyroid Gland

Thyroglossal Duct Cancer

Toxic Goitre Malignant Tumour

Cancerous Goitre

Renal Cell Carcinoma, Papillary, 1

Papillary Renal Cell Carcinoma

Hereditary Papillary Renal Cell Carcinoma

Papillary Renal Cell Carcinoma, Sporadic

Papillary Renal Cell Adenocarcinoma

RCCP

RCCP1

Renal Cell Carcinoma, Papillary

Renal Cell Carcinoma, Papillary, 1, Familial And Somatic

Chromophil Carcinoma Of Kidney

Papillary Kidney Carcinoma

Sporadic Papillary Renal Cell Carcinoma

Chromophil Renal Cell Carcinoma

Papillary Renal Carcinoma, Malignant -

Papillary Renal Cell Carcinoma, Bilateral -

Papillary Renal Cell Carcinoma, Familial -

Papillary Renal Cell Carcinoma, Multiple -

Papillary Renal Cell Carcinoma, Sporadic -

Renal Adenocarcinoma

Chromophil Rcc

Hprcc

Renal Cell Carcinoma Papillary

Chromophilic Renal Cell Carcinoma

Prcc

Carcinoma, Renal Cell, Papillary, Type 1

Type 1 Papillary Renal Cell Carcinoma

Renal Cell Carcinoma

Hereditary Papillary Renal Carcinoma

Urinary Bladder Small Cell Neuroendocrine Carcinoma

Small Cell Neuroendocrine Carcinoma Of The Urinary Bladder

Small Cell/Neuroendocrine Carcinoma Of Urinary Bladder

Obstructive Jaundice

Jaundice, Obstructive

Cholestatic Jaundice

Cholestatic Jaundice Syndrome

Obstructive Hyperbilirubinemia

Jaundice Obstructive

Jaundice Cholestatic

Anus Cancer

Anal Cancer

Anal Carcinoma

Malignant Anal Tumor

Cancer Of The Anus

Malignant Neoplasm Of Anus

Anus Neoplasms

Pulmonary Artery Leiomyosarcoma

Leiomyosarcoma Of The Pulmonary Artery

Thoracic Benign Neoplasm

Benign Neoplasm Of Thorax

Rectosigmoid Junction Neoplasm

Neoplasm Of Rectosigmoid Junction

Rectosigmoid Neoplasm

Rectosigmoid Tumor

Rectosigmoid Carcinoma

Carcinoma Of The Rectosigmoid Junction

Malignant Tumor Of Rectosigmoid Junction

Rectosigmoid Junction Cancer

Primary Malignant Neoplasm Of Rectosigmoid Junction

Rectosigmoid Colon Cancer

Carcinoma Of Rectum With Sigmoid

Colorectal Cancer Nos

Colorectal Carcinoma Nos

Rectosigmoid Cancer

Malignant Olfactory Nerve Neoplasm

Malignant Olfactory Nerve Tumor

Malignant Tumor Of Olfactory Nerve

Primary Malignant Neoplasm Of Olfactory Nerve

Respiratory System Benign Neoplasm

Renal Pelvis Carcinoma

Malignant Neoplasm Of Renal Pelvis

Malignant Tumor Of Renal Pelvis

Carcinoma Of Kidney Pelvis

Malignant Renal Pelvis Neoplasm

Renal Pelvis Cancer

Cystic Basal Cell Carcinoma

Skin Cystic Basal Cell Carcinoma

Chronic Pyelonephritis

Microinvasive Cervical Squamous Cell Carcinoma

Early Invasive Cervical Squamous Cell Carcinoma

Colorectal Adenocarcinoma

Adenocarcinoma Of Large Intestine

Skin Benign Neoplasm

Neoplasm Of Skin By Site

Tumor Of The Skin

Skin Tumor

Benign Neoplasm Of Skin

Skin Neoplasms

Mucinous Tubular And Spindle Renal Cell Carcinoma

Mucinous Tubular And Spindle Cell Renal Carcinoma

Cecal Disease

Cecal Diseases

Disorder Of Cecum

Adenosquamous Colon Carcinoma

Adenosquamous Carcinoma Of Colon

Colonic Adenosquamous Carcinoma

Colon Adenosquamous Carcinoma

Ovarian Large-Cell Neuroendocrine Carcinoma

Non-Small-Cell Type Neuroendocrine Carcinoma Of Ovary

Ovarian Large Cell Neuroendocrine Carcinoma

Pulmonary Adenocarcinoma In Situ

Bronchioalveolar Carcinoma

Basosquamous Carcinoma

Carcinoma, Basosquamous

Basisquamous Cell Carcinoma

Basosquamous Cell Carcinoma

Metatypical Carcinoma

Breast Benign Neoplasm

Benign Tumour Of Breast

Benign Neoplasm Of Female Breast

Vulvar Apocrine Adenocarcinoma

Vaginal Carcinosarcoma

Malignant Vaginal Mixed Epithelial And Mesenchymal Tumor

Vaginal Malignant Mixed Mesodermal Tumor

Vaginal Malignant Mixed Mullerian Tumor

Vaginal Mixed Epithelial And Mesenchymal Tumor

Breast Adenoid Cystic Carcinoma

Adenoid Cystic Breast Carcinoma

Adenoid Cystic Carcinoma Of Breast

Mammary Adenocystic Carcinoma

Rectal Disease

Rectal Diseases

Rectal Disorders

Heart Cancer

Malignant Neoplasm Of Heart

Heart Neoplasm

Cardiac Tumor

Malignant Cardiac Tumor

Tumour Of Heart

Heart Neoplasms

Cardiac Carcinoma

Vaginal Cancer

Malignant Neoplasm Of Vagina

Vaginal Neoplasms

Malignant Tumor Of Vagina

Malignant Vaginal Tumor

Neoplasm Of Vagina

Vagina Neoplasm

Vaginal Tumor

Vaginal Carcinoma

Vaginal Malignant Epithelial Tumor

Vaginal Neoplasm

Malignant Vaginal Neoplasm

Vagina Carcinoma

Vaginal Neoplasia

Cancer Of Vagina

Malignant Tumour Of Vagina

Carcinoma Of Vagina

Primary Malignant Neoplasm Of Vagina

Vagina Wall Cancer

Vaginal Wall Cancer

Sublingual Gland Adenoid Cystic Carcinoma

Vascular Cancer

Blood Vessel Tumors

Malignant Vascular Neoplasm

Renal Vein Leiomyosarcoma

Vascular Neoplasms

Blood Vessel Neoplasm

Blood Vessel Tumor

Blood Vessel Tumour Disorder

Haemangiomatous Tumour

Leiomyosarcoma Of The Renal Vein

Malignant Great Vessel Tumor

Malignant Tumor Of Pulmonary Artery

Malignant Tumor Of Pulmonary Vein

Malignant Vascular Tumor

Neoplasm Of Great Vessel

Pulmonary Artery Malignant Neoplasm

Pulmonary Vein Malignant Neoplasm

Vascular Tissue Neoplasm

Vascular Tumors

Blood Vessel Cancer

Neoplasms, Vascular Tissue

Malignant Neoplasm Of Great Vessels

Liver Sarcoma

Hepatic Sarcoma

Sarcoma Of Liver

Lung Carcinoma In Situ

Corneal Dystrophy, Posterior Polymorphous, 1

Posterior Polymorphous Corneal Dystrophy

Ppcd

Maumenee Corneal Dystrophy

Posterior Polymorphous Corneal Dystrophy 1

PPCD1

Corneal Dystrophy, Hereditary Polymorphous Posterior

Corneal Endothelial Dystrophy 1, Autosomal Dominant

Schlichting Dystrophy

Ched1

Corneal Endothelial Dystrophy 1, Autosomal Dominant, Formerly

Ched1, Formerly

Hereditary Polymorphus Posterior Corneal Dystrophy

Posterior Polymorphous Dystrophy

Hereditary Polymorphous Posterior Corneal Dystrophy

Dystrophy, Corneal, Posterior Polymorphous

Dystrophy, Corneal, Posterior Polymorphous, Type 1

Polymorphous Corneal Dystrophy

Corneal Endothelial Dystrophy 2

Birt-Hogg-Dube Syndrome

Hornstein-Knickenberg Syndrome

Fibrofolliculomas With Trichodiscomas And Acrochordons

BHD

Birt-Hogg-Dubé Syndrome

Multiple Fibrofolliculoma Familial

Bhd Syndrome

Birt Hogg Dube Syndrome

Hornstein-Birt-Hogg-Dubé Syndrome

Multiple Fibrofolliculomas

Basal Cell Carcinoma

Basal Cell Cancer

Basal Cell Neoplasm

Basal Cell Carcinoma Of Skin

Malignant Basal Cell Tumor

Basal Cell Tumor

Epithelioma Basal Cell

Malignant Basal Cell Neoplasm

Rodent Ulcer

Carcinoma Basal Cell

Neoplasms, Basal Cell

Basal Cell Carcinomas

Experimental Organism Basal Cell Carcinoma

Nodulo-Ulcerative Basal Cell Carcinoma

Basalioma

Basal Cell Epithelioma Of Skin

Bcc - [Basal Cell Carcinoma] Of Skin

Rodent Ulcer Of Skin

Rodent Ulcer Of Unspecified Site

Basal Cell Epithelioma Of Unspecified Site

Pheochromocytoma

Pheochromocytoma, Susceptibility To

Phaeochromocytoma

Adrenal Gland Chromaffin Paraganglioma

Adrenal Gland Chromaffinoma

Adrenal Gland Paraganglioma

Adrenal Gland Pheochromocytoma

Chromaffin Paraganglioma Of The Adrenal Gland

Intraadrenal Paraganglioma

PCC

Chromaffin Cell Tumor

Medullary Chromaffinoma

Medullary Paraganglioma

Pheochromoblastoma

Pheochromocytomas

Chromaffin Cell Neoplasm

Pheochromocytoma, Malignant

Ovarian Sex-Cord Stromal Tumor

Ovarian Sex Cord Tumor With Annular Tubules

Ovarian Sex Cord-Stromal Tumor

Stromal Tumor Of Ovary

Small Intestine Adenocarcinoma

Small Intestinal Adenocarcinoma

Adenocarcinoma Of Small Intestine

Adenocarcinoma Of The Small Bowel

Adenocarcinoma Of Small Bowel

Adenocarcinoma Of Small Instestine

Adenocarcinoma Of The Small Instestine

Small Bowel Adenocarcinoma

Adenocarcinoma Of The Small Intestine

Lacrimal Gland Mucoepidermoid Carcinoma

Mucoepidermoid Carcinoma Of The Lacrimal Gland

Hydrocele

Testicular Hydrocele

Endobronchial Lipoma

Papillary Squamous Carcinoma

Papillary Epidermoid Carcinoma

Papillary Squamous Cell Carcinoma

Rectal Benign Neoplasm

Neoplasm Of Rectum

Rectal Tumor

Rectum Neoplasm

Neoplasm Of The Rectum

Rectal Neoplasms

Primary Rectal Cancer

Rectal Ampulla Cancer

Cancer Of The Rectum

Carcinoma Of Rectum

Primary Malignant Neoplasm Of Rectum

Rectal Cancer

Rectal Carcinoma

External Ear Carcinoma

Carcinoma Of External Ear

Carcinoma Of The External Ear

Bladder Cancer

Urinary Bladder Cancer

Bladder Carcinoma

Urinary Bladder Carcinoma

Bladder Neoplasm

Bladder Tumor

Cancer, Bladder

Malignant Neoplasm Of Urinary Bladder

Carcinoma Of Bladder

Bladder Cancer, Somatic

Tumor Of The Bladder

Carcinoma Of Urinary Bladder

Bladder Carcinoma Urinary

Cancer Of The Urinary Bladder

Cancer, Urinary Bladder

Malignant Bladder Neoplasm

Malignant Bladder Tumor

Neoplasm Of The Bladder

Neoplasm Of The Urinary Bladder

Tumor Of The Urinary Bladder

Urinary Bladder Neoplasm

BLC

Urothelial Carcinoma Of The Bladder

Bladder Tumors

Urinary Bladder Neoplasms

Bladder Cancer Nos

Vesical Cancer Nos

Malignant Neoplasm Of Bladder, Part Unspecified

Malignant Tumour Of Urinary Bladder

Primary Malignant Neoplasm Of Bladder

Hemorrhoid

Hemorrhoids

Hemorrhoidal Disease

Rectal Diseases

Piles

Unspecified Haemorrhoids Without Complication

Bile Duct Disease

Bile Duct Diseases

Bile Duct Disorder

Disorder Of Bile Duct

Synovium Cancer

Malignant Tumor Of Synovium

Synovial Neoplasm

Endocervical Adenocarcinoma

Endocervical Carcinoma

Tibial Adamantinoma

Tibial Adamantinoma Morphology

Large Cell Acanthoma

Biliary Tract Disease

Biliary Tract Diseases

Biliary Tract Abnormality

Colonic Lymphangioma

Lymphangioma Of Colon

Colon Lymphangioma

Keratosis, Seborrheic

Seborrheic Keratosis

Keratosis, Seborrheic, Somatic

Basal Cell Papilloma

Keratosis Seborrheica

KERSEB

Mixed Epithelial Stromal Tumour

Endometrial Adenocarcinoma

Endometrial Endometrioid Adenocarcinoma

Endometrial Adenoacanthoma

Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation

Adenocarcinoma Of Endometrium

Adenocarcinoma Of The Endometrium

Adenocarcinoma Of Uterus

Endometrial Endometrioid Adenocarcinoma With Squamous Differentiation

Endometrioid Adenoma Or Carcinoma

Endometrioid Adenomas And Carcinomas

Endometrioid Carcinoma Of Endometrium

Endometrium Adenocarcinoma

Vaginal Discharge

Muir-Torre Syndrome

MRTES

Keratoacanthoma

Muir-Torré Syndrome

Cutaneous Sebaceous Neoplasms And Keratoacanthomas, Multiple, With Gastrointestinal And Other Carcinomas

Cutaneous Sebaceous Neoplasms And Keratoacanthomas Multiple With Gastrointestinal And Other Carcinomas

Multiple Keratoacanthoma, Muir-Torre Type

Mts

Torre-Muir Syndrome

Breast Hemangioma

Angioma Of The Breast

Hemangioma Of Breast

Haemangioma Of Breast

Rhabdomyosarcoma

Sublingual Gland Cancer

Malignant Tumor Of Sublingual Gland

Malignant Tumor Of The Sublingual Gland

Female Reproductive Endometrioid Cancer

Endometrioid Tumor

Endometrioid Neoplasm

Female Reproductive Endometrioid Neoplasm

Bile Duct Adenocarcinoma

Urinary Tract Obstruction

Obstructive Uropathy

Urinary Obstruction

Urologic Diseases

Nasal Cavity Olfactory Neuroblastoma

Olfactory Neuroblastoma Of The Nasal Cavity

Bartholin'S Gland Adenoid Cystic Carcinoma

Bartholin Gland Adenoid Cystic Carcinoma

Vaginal Adenoma

In Situ Carcinoma

Carcinoma In Situ

Nephrogenic Adenoma Of The Urethra

Nephrogenic Adenoma Of Urethra

Reproductive Organ Benign Neoplasm

Metatypical Basal Cell Carcinoma

Skin Metatypical Carcinoma

Basosquamous Carcinoma Of Skin

Skin Metatypical Basal Cell Carcinoma

Cervical Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma Of The Cervix Uteri

Pre-Malignant Neoplasm

Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Gastrointestinal System Benign Neoplasm

Rectum Adenocarcinoma

Rectal Adenocarcinoma

Adenocarcinoma Of Rectum

Uterus Perivascular Epithelioid Cell Tumor

Uterine Corpus Pecoma

Squamous Cell Bile Duct Carcinoma

Bile Duct Squamous Cell Carcinoma

Cardiovascular Organ Benign Neoplasm

Hydronephrosis

Stricture Of Ureteropelvic Junction With Hydronephrosis

Hydronephrosis With Ureteral Stricture, Not Elsewhere Classified

Thyroid Gland Follicular Carcinoma

Follicular Thyroid Carcinoma

Follicular Adenocarcinoma

Follicular Adenocarcinoma, Well Differentiated

Follicular Carcinoma

Thyroid Adenocarcinoma

Adenocarcinoma, Follicular

Synovium Neoplasm

Synovial Neoplasm

Tumor Of Synovium

Ureter Small Cell Carcinoma

Ureteral Small Cell Carcinoma

Squamous Papillomatosis

Vaginal Benign Neoplasm

Malignant Ovarian Surface Epithelial-Stromal Neoplasm

Malignant Ovarian Surface Epithelial-Stromal Tumor

Intrahepatic Gall Duct Cancer

Malignant Neoplasm Of Intrahepatic Bile Ducts

Malignant Neoplasm Of Intrahepatic Gall Duct

Ca Intrahepatic Bile Ducts

Malignant Neoplasm Of Intrahepatic Biliary Passages

Intrahepatic Bile Duct Carcinoma

Bile Duct Cystadenoma

Cystadenoma Of The Bile Duct

Thymus Large Cell Carcinoma

Large Cell Carcinoma Of The Thymus

Thymic Large Cell Neuroendocrine Carcinoma

Mixed Lacrimal Gland Cancer

Carcinoma Ex Pleomorphic Adenoma Of Lacrimal Gland

Carcinoma Ex Pleomorphic Adenoma Of The Lacrimal Gland

Malignant Mixed Neoplasm Of Lacrimal Gland

Lymphangioma

Lymphatic Malformation

Lymphatic Malformations

Benign Lymphangioma

Congenital Lymphangioma

Lymphangiomas

Cervix Carcinoma

Cancer Of Cervix

Carcinoma Of Cervix

Carcinoma Cervix Uteri

Carcinoma Of The Cervix Uteri

Gallbladder Disease

Gallbladder Diseases

Gall Bladder

Gall Bladder Diseases

Abnormal Gallbladder Function

Mediastinum Sarcoma

Sarcoma Of Mediastinum

Ovarian Serous Cystadenofibroma

Retinal Melanoma

Malignant Retinal Melanoma

Malignant Melanoma Of Retina

Vulvar Proximal-Type Epithelioid Sarcoma

Central Epithelioid Sarcoma

Proximal-Type Epithelioid Sarcoma

Inflammatory Myofibroblastic Tumor

Inflammatory Fibrosarcoma

Cholangitis, Primary Sclerosing

Primary Sclerosing Cholangitis

PSC

Sclerosing Cholangitis

Cholangitis, Sclerosing

Cholangitis Primary Sclerosing

Psc - [Primary Sclerosing Cholangitis]

Benign Peritoneal Mesothelioma

Mesothelioma Of Peritoneum

Benign Neoplasm Of Mesothelial Tissue Of Peritoneum

Epithelioid Cell Synovial Sarcoma

Synovial Sarcoma, Epithelioid Cell

Epithelioid Synovial Sarcoma

Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor

Micronodular Basal Cell Carcinoma

Skin Micronodular Basal Cell Carcinoma

Basal Cell Carcinoma, Micronodular

Colonic Benign Neoplasm

Colon Neoplasm

Colonic Mass

Colonic Tumor

Neoplasm Of Colon

Neoplasm Of The Colon

Colonic Neoplasms

Colon Cancer

Colon Carcinoma Nos

Colonic Cancer

Metastatic Colon Cancer Nos

Lynch Syndrome

Hereditary Nonpolyposis Colon Cancer

Hereditary Nonpolyposis Colorectal Cancer

Hereditary Nonpolyposis Colorectal Carcinoma

Hereditary Nonpolyposis Colorectal Neoplasms

Familial Nonpolyposis Colon Cancer

Hnpcc

Coca 1

Hereditary Defective Mismatch Repair Syndrome

Hereditary Non-Polyposis Colon Cancer

Hereditary Non-Polyposis Colon Cancer Syndrome

Hereditary Non-Polyposis Colorectal Cancer

Hereditary Non-Polyposis Colorectal Cancer Syndrome

Hereditary Nonpolyposis Colon Cancer Syndrome

Hereditary Nonpolyposis Colorectal Cancer Syndrome

Hereditary Nonpolyposis Colorectal Neoplasm

Hnpcc - Hereditary Nonpolyposis Colon Cancer

Cancer Family Syndrome

Familial Nonpolyposis Colorectal Cancer

Colon Cancer, Familial Nonpolyposis

Colorectal Neoplasms, Hereditary Nonpolyposis

Cancer, Colorectal, Nonpolyposis, Hereditary

Colorectal Cancer, Hereditary Nonpolyposis, Type 1

疾病名称

别名

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

直系同源

种属

基因名

来源

基因 ID

Mus musculus

KRT7

MGD

MGI:96704

Felis catus

KRT7

VGNC

VGNC:67991

Rattus norvegicus

KRT7

RGD

RGD:1310865

Macaca mulatta

KRT7

VGNC

VGNC:74214

Bos taurus

KRT7

VGNC

VGNC:30734

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实体化合物库

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虚拟筛选

Customize Your Library

定制专属化合物库

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pan Cytokeratin抗体[KRT/1877R]| Abcam中文官网

pan Cytokeratin抗体[KRT/1877R]| Abcam中文官网

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Signal Transduction Cytoskeleton / ECM Cytoskeleton Intermediate Filaments Class I Cytokeratins

Anti-pan Cytokeratin抗体[KRT/1877R] (ab234297)

Datasheet

SDS

Reviews (6)

Submit a question

References (4)

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Key features and details

Rabbit monoclonal [KRT/1877R] to pan Cytokeratin

Suitable for: ICC, IHC-P

Reacts with: Human

Isotype: IgG

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概述

产品名称

Anti-pan Cytokeratin抗体[KRT/1877R]参阅全部 pan Cytokeratin 一抗

描述

兔单克隆抗体[KRT/1877R] to pan Cytokeratin

宿主

Rabbit

经测试应用

适用于:

ICC, IHC-Pmore details

种属反应性

与反应:

Human预测可用于:

Mouse, Rat, Goat, Guinea pig, Cow, Pig, Monkey

免疫原

Tissue, cells or virus corresponding to Human pan Cytokeratin. (Keratin-enriched preparation from cultured human epithelial cells).

阳性对照

IHC-P: Human skin tissue.

ICC: MCF7 cells

常规说明

The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

形式

Liquid

存放说明

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

存储溶液

pH: 7.2Preservative: 0.05% Sodium azideConstituents: PBS, 0.05% BSA

Concentration information loading...

纯度

Protein A/G purified

纯化说明

Purified from Bioreactor Concentrate by Protein A/G.

克隆

单克隆

克隆编号

KRT/1877R

同种型

IgG

研究领域

Signal Transduction

Cytoskeleton / ECM

Cytoskeleton

Intermediate Filaments

Class I

Cytokeratins

相关产品

Alternative Versions

Anti-pan Cytokeratin antibody [KRT/1877R] - BSA and Azide free (ab236323)

Compatible Secondaries

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)

Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Isotype control

Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730)

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab234297于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

应用

Ab评论

说明

ICC

Use a concentration of 1 - 2 µg/ml.

IHC-P

(4)

Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Primary incubation for 30 minutes at room temperature.

说明

ICCUse a concentration of 1 - 2 µg/ml.

IHC-PUse a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Primary incubation for 30 minutes at room temperature.

靶标

相关性

Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micrometastases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors.

There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.

细胞定位

Cytoplasmic

数据库链接

Entrez Gene:

374454 Human

Entrez Gene:

51350 Human

SwissProt:

Q01546 Human

SwissProt:

Q7Z794 Human

别名

pan ck antibody

pan-ck antibody

panck antibody

图片

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-pan Cytokeratin antibody [KRT/1877R] (ab234297)

Formalin-fixed, paraffin-embedded human skin tissue stained for pan Cytokeratin using ab234297 at 1 μg/ml in immunohistochemical analysis.

Immunocytochemistry - Anti-pan Cytokeratin antibody [KRT/1877R] (ab234297)

Immunocytochemistry analysis of MCF7 cells labeling pan Cytokeratin with ab234297 at 2ug/mL followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red).

实验方案

To our knowledge, customised protocols are not required for this product.

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文献 (4)

发表研究结果有使用 ab234297？请让我们知道，以便我们可以引用本数据表中的参考文章。

ab234297 被引用在 4 文献中.

Moon H  et al. Activated TAZ induces liver cancer in collaboration with EGFR/HER2 signaling pathways. BMC Cancer 22:423 (2022).

PubMed: 35439973

Huang N  et al. SARS-CoV-2 infection of the oral cavity and saliva. Nat Med 27:892-903 (2021).

PubMed: 33767405

Xu L  et al. MEF/KSF-conditioned culture medium: An effective method for in vitro culture of mouse dermal papilla cells with osteogenic differentiation potential. Exp Ther Med 22:828 (2021).

PubMed: 34149874

Huang N  et al. Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis. medRxiv N/A:N/A (2020).

PubMed: 33140061

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IHC - Wholemount abreview for Anti-pan Cytokeratin antibody [KRT/1877R]

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Mouse Tissue (Embryonic Kidney)

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Lauren Russell

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Immunohistochemistry (Frozen sections) abreview for Anti-pan Cytokeratin antibody [KRT/1877R]

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Immunohistochemistry (Frozen sections)

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Mouse Tissue sections (Tumor)

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Tumor

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(agent) for 30 minute(s) · Concentration: 0.25% · Temperature: 25°C

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Formaldehyde

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-pan Cytokeratin antibody [KRT/1877R]

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Endometrium

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Peroxide block as blocking agent for 5 minute(s) · Concentration: 3% · Temperature: 20°C

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Formaldehyde

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The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-pan Cytokeratin antibody [KRT/1877R]

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Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 22°C

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Formaldehyde

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-pan Cytokeratin antibody [KRT/1877R]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

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Heat mediated - Buffer/Enzyme Used: Tris-EDTA buffer, pH 9.0, citrate pH 6.

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Yes - 0.2% Triton-PBS

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skin

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Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 22°C

Fixative

Formaldehyde

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The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

Josune Garcia

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提交于 Oct 01 2019

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-pan Cytokeratin antibody [KRT/1877R]

Excellent

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

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Mouse Tissue sections (Lung)

Antigen retrieval step

Heat mediated

Permeabilization

No

Specification

Lung

Blocking step

Protein Block from ab236469 as blocking agent for 10 minute(s) · Concentration: 100% · Temperature: 22°C

Fixative

Formaldehyde

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The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

Abcam user community

Verified customer

提交于 Mar 28 2019

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中国医学科学院JBC食管癌最新研究 - 生物通

中国医学科学院JBC食管癌最新研究 - 生物通

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生物通首页  >  今日动态  >  正文

中国医学科学院JBC食管癌最新研究

【字体：

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时间：2015年04月09日

来源：生物通

编辑推荐：

　　四月七日，国际著名学术期刊《Journal of Biological Chemistry》发表了中国医学科学院和美国匹茨堡大学的一项最新研究成果。这项研究表征了KLF4-KRT13和食管鳞状细胞癌分化之间的一种关键联系，并为KLF4 受KRT13调控的机制提供了深刻的见解。该研究还阐明了KLF4-KRT13信号通路在SB介导的食管癌细胞分化过程中的重要性。

　　生物通报道：四月七日，国际著名学术期刊《Journal of Biological Chemistry》发表了中国医学科学院和美国匹茨堡大学的一项最新研究成果，题为“Kruppel like factor 4 promotes esophageal squamous cell carcinoma differentiation by upregulating keratin 13 expression”。 这项研究表征了KLF4-KRT13和食管鳞状细胞癌分化之间的一种关键联系，并为KLF4 受KRT13调控的机制提供了深刻的见解。该研究还阐明了KLF4-KRT13信号通路在SB介导的食管癌细胞分化过程中的重要性。

本文通讯作者是中国医学科学院北京协和医学院肿瘤医院分子肿瘤学国家重点实验室刘芝华研究员，教育部“****奖励计划”特聘教授，国家杰出青年基金获得者。刘芝华研究员1987年毕业于北京大学，1993年在北京大学获博士学位，1993年至1996年在美国华盛顿州立大学从事博士后研究，1997年至今在分子肿瘤学国家重点实验室工作。刘芝华带领的课题组主要致力于食管癌、乳腺癌等常见恶性肿瘤的发病机理研究，涉及的研究领域主要包括肿瘤转移、肿瘤微环境、肿瘤抗药性以及肿瘤标志物和分子靶标等。该科研团队曾经发现孟德尔隐性主基因对食管癌发生起决定性作用，并阐释了遗传因素在食管癌变过程中的重要作用，科研成果曾经发表在Clin Cancer Res、Cancer Res、JBC等知名期刊。

食管癌是一种侵袭性的疾病，倾向于局部病灶和远端蔓延，是导致全球癌症相关死亡的第六大原因。根据不同的组织学、遗传学和表遗传学改变和癌起源地，将食管癌分为几种亚型，可致使手术切除、放疗和化疗后有不同的预后结果。食管癌最常分布在东亚国家。虽然在局部控制率和长期生存率方面，手术是食管癌的最佳治疗，但在大多数接受完整肿瘤切除术的病例中，会发生复发和肝转移，从而导致只有25%的5年生存率。目前缺乏有效的靶向治疗，对标准化疗的反应也较差，往往归因于这种疾病迅速致命的预后。因此，我们需要理解驱动ESCC的分子机制，并将这方面的知识转化为新的、令人鼓舞的干预策略和治疗选择。延伸阅读：中国医学科学院食管癌基因组研究取得重大突破。

鳞状细胞分化需要特定于分化过程的基因的协同活化和抑制，这一程序的中断伴有恶性上皮细胞转化。探索控制表皮细胞增殖和终末分化的基因，对于我们更好地了解食管癌变至关重要。

KLF4是KLF转录因子家族成员，参与细胞的增殖和分化。KRT是一个中间丝状体蛋白家族，以一种细胞类型特异性和分化依赖性的方式在上皮细胞中表达。越来越多的证据表明，个体KRTs在各种各样肿瘤中的差异表达，使得它们成为组织病理学癌亚型的有用标记，并提供了关于肿瘤分化状态和起源的相关信息，尤其是转移性肿瘤。

这项研究使用免疫组化法，对食管鳞状细胞癌（ESCC）临床标本中的KLF4进行了分析，发现KLF4减少与肿瘤低分化明显相关。此外，该研究确定，当丁酸钠（SB）诱导食管癌分化和G1期阻滞时，KLF4和KRT13的水平无疑是增强的。相反，抑制KLF4和KRT13可解除SB诱导的G1-S转换抑制。分子研究表明，KLF4可转录调节KRT13，并且在食管鳞癌组织和细胞系中，这两个分子的表达是明显相关的。

总的来说，这些结果表征了KLF4-KRT13和ESCC分化之间的一种关键联系，并为KLF4 受KRT13调控的机制提供了深刻的见解。该研究还阐明了KLF4-KRT13信号通路在SB介导的食管癌细胞分化过程中的重要性。因此，这项研究，为通过具体评价KLF4 和 KRT13表达变化识别ESCC恶性进展的新生物标志物，打开了一条独特的途径。

（生物通：王英）

生物通推荐原文摘要：Kruppel like factor 4 promotes esophageal squamous cell carcinoma differentiation by upregulating keratin 13 expressionAbstract：Squamous cell differentiation requires the coordinated activation and repression of genes specific to the differentiation process, disruption of this program accompanies malignant transformation of epithelium. The exploration of genes which control epidermal proliferation and terminal differentiation is vital to better understand esophageal carcinogenesis. KLF4 is a member of the KLF family of transcription factors and involved in both cellular proliferation and differentiation. The present study using immunohistochemistry analysis of KLF4 in clinical specimens of esophageal squamous cell carcinoma (ESCC) exhibited that decreased KLF4 was substantially associated with poor differentiation. Moreover, we determined that both KLF4 and KRT13 level were undoubtedly augmented upon sodium butyrate (SB) induced ESCC differentiation and G1-phase arrest. Conversely, silencing of KLF4 and KRT13 abrogated the inhibition of G1-S transition induced by SB. Molecular investigation demonstrated that KLF4 transcriptionally regulated KRT13 and the expression of the two molecules appreciably correlated in ESCC tissues and cell lines. Collectively, these results suggest that KLF4 transcriptionally regulates KRT13 and involves in ESCC cell differentiation.

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